Current progress in medical mycology /

Current progress in medical mycology /

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Bibliographic Details
Imprint:Cham, Switzerland : Springer, [2017]
©2017
Description:1 online resource : illustrations
Language:English
Subject:
Medical mycology.
Mycology.
Medical mycology.
Mycology.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11384627
Hidden Bibliographic Details
Other authors / contributors:Mora-Montes, Hector Manuel, editor.
Lopes-Bezerra, Leila M., editor.
ISBN:9783319641133
3319641131
9783319641126
3319641123
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Online resource; title from PDF title page (EBSCO, viewed November 02, 2017).
Summary:Infections caused by fungi have recently attracted the attention of both clinicians and basic researchers given the heavy burden they represent for any health system. The mortality and morbidity rates associated to mycosis are progressively rising simply because some of these diseases are still neglected by health-care workers and due to the changing sensitivity to antifungal drugs displayed by these organisms. In this book, both researchers and clinicians working in the medical mycology field explore the most recent literature about specific mycosis; placing in one concise chapter thoroughly revisions of the current knowledge on virulence factors, recognition by immune cells, immunoevasion, epidemiology, new diagnosis trends and therapeutics. This book is recommended to researchers, physicians and students interested in medical mycology.
Other form:Print version: Current progress in medical mycology. Cham, Switzerland : Springer, [2017] 9783319641126 3319641123
Standard no.:10.1007/978-3-319-64113-3
Table of Contents:
  • Preface
  • Contents
  • Contributors
  • Chapter 1: Introduction to Medical Mycology
  • 1.1 Definition and Structure
  • 1.2 Emergence of Challenge Due to Fungal Infections
  • 1.3 Spectrum of Fungal Infections
  • 1.3.1 Superficial Mycoses
  • 1.3.2 Invasive/Opportunistic Mycoses
  • 1.3.3 Endemic Mycoses
  • 1.3.4 Allergic Manifestations
  • 1.4 Classification
  • 1.5 Epidemiology of Fungal Infections
  • 1.5.1 Global Burden of Disease
  • 1.5.2 Predisposing Factors for Fungal Infections
  • 1.5.3 Geographical Distribution
  • 1.5.4 Community Acquired Fungal Infections1.5.5 Nosocomial Fungal Infections
  • 1.6 Fungal Infection Immunity and Pathogenesis
  • 1.6.1 Innate Immunity
  • 1.6.2 Adaptive Immunity
  • 1.6.3 Fungal Virulence
  • 1.6.4 Tissue Reaction
  • 1.7 Diagnosis of Fungal Infections
  • 1.7.1 Radiological Imaging
  • 1.7.2 Conventional and Culture Based Diagnosis
  • 1.7.3 Sepsis Biomarkers
  • 1.7.4 Serology
  • 1.7.5 Molecular Detection
  • 1.8 Treatment
  • 1.9 Fungal Vaccines
  • References
  • Chapter 2: Antifungal Drugs
  • 2.1 Polyenes (Amphotericin B Deoxycholate and Its Lipid-ÂƯAssociated Formulations)2.1.1 Amphotericin B Deoxicholate
  • 2.1.1.1 Chemical Structure
  • 2.1.1.2 Mechanism of Action
  • 2.1.1.3 Pharmacokinetics and Pharmacodynamics
  • 2.1.1.4 Spectrum of Activities and Resistance
  • 2.1.1.5 Clinical Uses
  • 2.1.1.6 Dosing
  • 2.1.1.7 Adverse Events and Toxicity
  • 2.1.1.8 Contraindication
  • 2.1.1.9 Drug Interactions
  • 2.1.1.10 Use in Special Population
  • 2.1.2 Lipid Formulations of Amphotericin B
  • 2.1.2.1 Dosing
  • 2.1.2.2 Adverse Events and Toxicity
  • 2.2 Triazole Antifungal Agents2.2.1 General Properties
  • 2.2.1.1 Chemical Structure
  • 2.2.1.2 Mechanism of Action
  • 2.2.1.3 Pharmacokinetics
  • 2.2.1.4 Spectrum of Activity and Resistance
  • 2.2.1.5 Clinical Utility
  • 2.2.1.6 Adverse Events and Drug Interactions
  • 2.2.1.7 Dosing and Administration. Use in Special Populations
  • 2.2.2 Individual Agents
  • 2.2.2.1 Itraconazole
  • 2.2.2.2 Fluconazole
  • 2.2.2.3 Voriconazole
  • 2.2.2.4 Posaconazole
  • 2.2.2.5 Isavuconazole
  • 2.2.3 Newer and Investigational Agents: Efinaconazole, Albaconazole, Ravuconazole and Others2.3 Echinocandins
  • 2.3.1 Chemical Structure
  • 2.3.2 Mechanism of Action
  • 2.3.3 Pharmacokinetics and Pharmacodynamics
  • 2.3.4 Spectrum of Activity and Resistance
  • 2.3.5 Clinical Uses
  • 2.3.6 Adverse Events and Toxicity
  • 2.3.7 Drug Interactions
  • 2.3.8 Use in Special Population and Dose Adjustments
  • 2.3.9 Adult Dosing
  • 2.3.10 New Echinocandin
  • 2.4 Flucytosine
  • 2.4.1 Chemical Structure
  • 2.4.2 Mechanism of Action

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