Retinal gene therapy : methods and protocols /
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Imprint: | New York, NY : Humana Press : Springer, [2018] ©2018 |
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Description: | 1 online resource (xvi, 380 pages) : illustrations (some color) |
Language: | English |
Series: | Methods in molecular biology ; v. 1715 Methods in molecular biology (Clifton, N.J.) ; v. 1715. |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11389354 |
Table of Contents:
- Small scale production of recombinant adeno-associated viral vectors for gene delivery to the nervous system / Joost Verhaagen, Barbara Hobo, Erich M.E. Ehlert, Ruben Eggers, Joanna A. Korecka, Stefan A. Hoyng, Callan L. Attwell, Alan R. Harvey, and Matthew R.J. Mason
- Small and micro-scale recombinant adeno-associated virus production and purification for ocular gene therapy applications / Christopher A. Reid and Daniel M. Lipinski
- Design and development of AAV-based gene supplementation therapies for achromatopsia and retinitis pigmentosa / Christian Schön, Elvir Becirovic, Martin Biel, and Stylianos Michalakis
- Development of multigenic lentiviral vectors for cell-specific expression of antiangiogenic miRNAs and protein factors / Anne Louise Askou and Thomas J. Corydon
- Design and in vitro use of antisense oligonucleotides to correct pre-mRNA splicing defects in inherited retinal dystrophies / Alejandro Garanto and Rob W.J. Collin
- Three-dimensional co-culture bioassay for screening of retinal gene delivery systems / Ding Wen Chen, Kathleen Pauloff, and Marianna Foldvari
- Retinal gene therapy for choroideremia : in vitro testing for gene augmentation using an adeno-associated viral (AAV) vector / Maria I. Patrício and Robert E. MacLaren
- In vivo electroporation of developing mouse retina / Jimmy de Melo and Seth Blackshaw
- Methods for in vivo CRISPR/Cas editing of the adult murine retina / Sandy S. Hung, Fan Li, Jiang-Hui Wang, Anna E. King, Bang V. Bui, Guei-Sheung Liu, and Alex W. Hewitt
- AAV gene augmentation therapy for CRB1-associated retinitis pigmentosa / C. Henrique Alves and Jan Wijnholds
- Dual AAV vectors for stargardt disease / Ivana Trapani-- Optogenetic retinal gene therapy with the light gated GPCR vertebrate rhodopsin / Benjamin M. Gaub, Michael H. Berry, Meike Visel, Amy Holt, Ehud Y. Isacoff, and John G. Flannery
- CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa : a brief methodology / Wen-Hsuan Wu, Yi-Ting Tsai, Sally Justus, Galaxy Y. Cho, Jesse D. Sengillo, Yu Xu, Thiago Cabral, Chyuan-Sheng Lin, Alexander G. Bassuk, Vinit B. Mahajan, and Stephen H. Tsang
- In-depth functional analysis of rodents by full-field electroretinography / Vithiyanjali Sothilingam, Regine Mühlfriedel, Naoyuki Tanimoto, and Mathias W. Seeliger
- Advanced ocular injection techniques for therapy approaches / Regine Mühlfriedel, Marina Garcia Garrido, Christine Wallrapp, and Mathias W. Seeliger
- Neutralizing antibodies against adeno-associated virus (AAV) : measurement and influence on retinal gene delivery / Mélissa Desrosiers and Deniz Dalkara
- Screening for neutralizing antibodies against natural and engineered AAV capsids in nonhuman primate retinas / Timothy P. Day, Leah C. Byrne, John G. Flannery, and David V. Schaffer
- Subretinal and intravitreal retinal injections in monkeys / Daniyar Dauletbekov, K. Ulrich Bartz-Schmidt, and M. Dominik Fischer
- Production of iPS-derived human retinal organoids for use in transgene expression assays / Peter M. Quinn, Thilo M. Buck, Charlotte Ohonin, Harald M.M. Mikkers, and Jan Wijnholds
- AAV serotype testing on cultured human donor retinal explants / Thilo M. Buck, Lucie P. Pellissier, Rogier M. Vos, Elon H.C. van Dijk, Camiel J.F. Boon, and Jan Wijnholds
- Human retinal explant culture for ex vivo validation of AAV gene therapy / Harry O. Orlans, Thomas L. Edwards, Samantha R. De Silva, Maria I. Patrício, and Robert E. MacLaren
- Visual acuity testing before and after intravitreal injection of rAAV2-ND4 in patients / Bin Li and Chenmian Wu
- Recording and analysis of the human clinical electroretinogram / Mathieu Gauvin, Allison L. Dorfman, and Pierre Lachapelle
- Recording and analysis of goldmann kinetic visual fields / Mays Talib, Gislin Dagnelie, and Camiel J.F. Boon
- Measuring central retinal sensitivity using microperimetry / Mays Talib, Jasleen K. Jolly, and Camiel J.F. Boon
- Inspection of the human retina by optical coherence tomography / Thomas Theelen and Michel M. Teussink
- Vector shedding and immunogenicity sampling for retinal gene therapy / Alun R. Barnard, Anna N. Rudenko, and Robert E. MacLaren.