Translational research in breast cancer : biomarker diagnosis, targeted therapies and approaches to precision medicine /

Translational research in breast cancer : biomarker diagnosis, targeted therapies and approaches to precision medicine /

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Bibliographic Details
Imprint:Singapore, Singapore : Springer, [2017]
Description:1 online resource (viii, 418 pages) : illustrations (some color)
Language:English
Series:Advances in experimental medicine and biology, 2214-8019 ; volume 1026
Advances in experimental medicine and biology ; v. 1026.
Subject:
Breast -- Cancer.
Breast -- Cancer -- Diagnosis.
Breast -- Cancer -- Treatment.
Biochemical markers.
Breast Neoplasms.
Translational Medical Research.
Breast Neoplasms -- therapy.
Precision Medicine -- methods.
Biochemical markers.
Breast -- Cancer.
Breast -- Cancer -- Diagnosis.
Breast -- Cancer -- Treatment.
Electronic book.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11399607
Hidden Bibliographic Details
Other authors / contributors:Song, Erwei, editor.
Hu, Hai, editor.
ISBN:9789811060205
9811060207
9789811060199
9811060193
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Online resource; title from electronic title page (SpringerLink, viewed April 13, 2018).
Summary:"This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. As a result of these two trends, a clearer picture of the molecular landscape of breast cancers has facilitated the development of diagnostic, prognostic and predictive biomarkers for clinical oncology. All these aspects are addressed in this volume, which offers a comprehensive resource for researchers, graduate students and oncologists in cancer research"--Publisher's description.
Other form:Print version: Translational research in breast cancer : biomarker diagnosis, targeted therapies and approaches to precision medicine. Singapore : Springer, [2017] 9789811060199
Standard no.:10.1007/978-981-10-6020-5
Table of Contents:
  • The dawning of translational breast cancer: from bench to bedside / Xueman Chen, Siting Fan, Erwei Song
  • Biomarker studies in early detection and prognosis of breast cancer / Gang Li, Jing Hu, Guohong Hu
  • The preventive intervention of hereditary breast cancer / Ayong Cao, Liang Huang, Zhimin Shao
  • Predicting and overcoming chemotherapeutic resistance in breast cancer / Kyung-Hee Chun, Jong Hoon Park, Siting Fan
  • Studies on DNA damage repair and precision radiotherapy for breast cancer / Yanhui Jiang, Yimin Liu, Hai Hu
  • Targeted therapies against growth factor signaling in breast cancer / Juan Du, Yu Yu, Jun Zhan, Hongquan Zhang
  • Targeting stemness: implications for precision medicine in breast cancer / Zhi-Mei Liang, Yang Chen, Man-Li Luo
  • Disrupting tumor angiogenesis and "the Hunger Games" for breast cancer / Ziwei Zhou, Herui Yao, Hai Hu
  • Key factors in breast cancer dissemination and establishment at the bone: past, present and future perspectives / Sioned Owen, Catherine Zabkiewicz, Lin Ye, Andrew J. Sanders, Chang Gong, Wen G. Jiang
  • Perspectives of reprogramming breast cancer metabolism / Yi-Ping Wang, Qun-Ying Lei
  • Metabolic changes during cancer cachexia pathogenesis / Ng Shyh-Chang
  • Cell cycle regulation in treatment of breast cancer / Zijie Cai, Qiang Liu
  • BRCA gene mutations and poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer / Hitomi Sumiyoshi Okuma, Kan Yonemori
  • Targeting the epigenome as a novel therapeutic approach for breast cancer / Sumin Oh, Je Yeong Ko, Chaeun Oh, Kyung Hyun Yoo
  • Progress in vaccine therapies for breast cancer / Xiaoyu Li, Xia Bu
  • Tumor associated macrophages as therapeutic targets for breast cancer / Liyan Lao, Siting Fan, Erwei Song
  • New approaches in CAR-T cell immunotherapy for breast cancer / Jinghua Wang, Penghui Zhou
  • Immune checkpoint blockade in breast cancer therapy / Xia Bu, Yihui Yao, Xiaoyu Li
  • Strategies and progress of endocrine therapy for patients with metastatic breast cancer / Hope S. Rugo, Huiping Li, Xinyu Gui.

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