Disease gene identification : methods and protocols /
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| Edition: | Second edition |
|---|---|
| Imprint: | New York, NY : Humana Press : Springer, [2018] ©2018 |
| Description: | 1 online resource (x, 400 pages) : illustrations (some color) |
| Language: | English |
| Series: | Methods in molecular biology, 1940-6029 ; 1706 Methods in molecular biology (Clifton, N.J.) ; v. 1706. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11455178 |
Table of Contents:
- Identification of disease susceptibility alleles in the next generation sequencing era / Johanna K. DiStefano and Christopher B. Kingsley
- Induced pluripotent stem cells in disease modeling and gene identification / Satish Kumar, John Blangero, and Joanne E. Curran
- Development of targeted therapies based on gene modification / Taylor M. Benson, Fatjon Leti, and Johanna K. DiStefano
- What can we learn about human disease from the nematode C. elegans / Javier Apfeld and Scott Alper
- Microbiome sequencing methods for studying human diseases / Rebecca M. Davidson and L. Elaine Epperson
- Emerging role of long noncoding RNAs in human disease / Johanna K. DiStefano
- Identification of disease-related genes using a genome-wide association study approach / Tobias Wohland and Dorit Schleinitz
- Whole genome library construction for next generation sequencing / Jonathan J. Keats, Lori Cuyugan, Jonathan Adkins, and Winnie S. Liang
- Whole exome library construction for next generation sequencing / Winnie S. Liang, Kristi Stephenson, Jonathan Adkins, Austin Christofferson, Adrienne Helland, Lori Cuyugan, and Jonathan J. Keats
- Optimized methodology for the generation of RNA-sequencing libraries from low-input starting material : enabling analysis of specialized cell types and clinical samples / Kendra Walton and Brian P. O'Connor
- Using fluidigm C1 to generate single-cell full-length cDNA libraries for mRNA sequencing / Robert Durruthy-Durruthy and Manisha Ray
- MiSeq : a next generation sequencing platform for genomic analysis / Rupesh Kanchi Ravi, Kendra Walton, and Mahdieh Khosroheidari
- Methods for CpG methylation array profiling via bisulfite conversion / Fatjon Leti, Lorida Llaci, Ivana Malenica, and Johanna K. DiStefano
- miRNA quantification method using quantitative polymerase chain reaction in conjunction with Cq method / Fatjon Leti and Johanna K. DiStefano
- Primary airway epithelial cell gene editing using CRISPR-Cas9 / Jamie L. Everman, Cydney Rios, and Max A. Seibold
- RNA interference to knock down gene expression / Haiyong Han
- Using luciferase reporter assays to identify functional variants at disease-associated loci / Anup K. Nair and Leslie J. Baier
- Physiologic interpretation of GWAS signals for type 2 diabetes / Richard M. Watanabe
- Identification of Genes for Hereditary Hemochromatosis / Glenn S. Gerhard, Barbara V. Paynton, and Johanna K. DiStefano
- Identification of driver mutations in rare cancers : the role of SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) / Jessica D. Lang and William P.D. Hendricks
- Rise and fall and rise of linkage analysis as a technique for finding and characterizing inherited influences on disease expression / Ettie M. Lipner and David A. Greenberg.