Design and evaluation of plasmonic/magnetic Au-MFe2O4 (M-Fe/Co/Mn) core-shell nanoparticles functionalized with doxorubicin for cancer therapeutics /
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| Author / Creator: | Manisekaran, Ravichandran. |
|---|---|
| Imprint: | Cham : Springer, ©2018. |
| Description: | 1 online resource (199 pages) |
| Language: | English |
| Series: | Springer theses Springer theses. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11542230 |
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| 100 | 1 | |a Manisekaran, Ravichandran. | |
| 245 | 1 | 0 | |a Design and evaluation of plasmonic/magnetic Au-MFe2O4 (M-Fe/Co/Mn) core-shell nanoparticles functionalized with doxorubicin for cancer therapeutics / |c Ravichandran Manisekaran. |
| 260 | |a Cham : |b Springer, |c ©2018. | ||
| 300 | |a 1 online resource (199 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 338 | |a online resource |b cr |2 rdacarrier | ||
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| 490 | 1 | |a Springer theses | |
| 500 | |a "Doctoral thesis accepted by Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Mexico City." | ||
| 505 | 0 | |a Dedication -- Supervisor#x80;#x99;s Foreword -- Preface -- Compilation Thesis -- Acknowledgements -- Contents -- List of Figures -- List of Tables -- Abbreviations -- List of Symbols -- Chapter 1: Introduction to Nanomedicine and Cancer Therapy -- 1.1 Introduction -- 1.1.1 Nanomedicine -- 1.1.2 Cancer Therapy -- 1.1.3 Essential Properties of Nanoparticles for Therapeutic Purpose and Their Applications in Cancer -- 1.1.3.1 Essential Properties of Nanoparticles for Therapeutic Purpose -- 1.1.3.1.1 Nanoparticle as Scaffolds | |
| 505 | 8 | |a 1.1.3.1.2 Surface Area of Nanoparticles1.1.3.1.3 Size Matters! -- 1.1.3.1.4 Shape of a Nanoparticle -- 1.1.3.1.5 Optical Properties -- 1.1.3.1.6 Magnetic Properties -- 1.1.3.1.7 Nanoparticles Platform -- 1.1.3.2 Applications of Nanomaterials in Cancer -- 1.1.3.2.1 Cancer Detection -- 1.1.3.2.1.1 MR Imaging -- Working Principle of MRI -- MR Imaging Parameters -- Relaxations -- 1.1.3.2.1.2 Computed Tomography (CT) -- 1.1.3.2.1.3 Optical Imaging -- 1.1.3.2.2 Nanopharmacotherapy -- 1.1.3.2.2.1 Targeted Therapy -- 1.1.3.2.2.2 Controlled Release | |
| 505 | 8 | |a 1.1.3.2.3 Nanotherapies1.1.3.2.3.1 Drug Delivery -- 1.1.3.2.3.2 Photothermal Therapy (PTT) -- 1.1.3.2.3.3 Hyperthermia/Magnetocytolytic Therapy -- 1.1.3.2.3.4 Thermal Ablation Therapy* -- Microwave Ablation (MwA) -- 1.1.4 Motivation and Outline of the Thesis -- 1.1.4.1 Motivation -- 1.1.4.2 Outline of the Thesis -- References -- Chapter 2: Literature Survey on Magnetic, Gold, and Core-Shell Nanoparticles -- 2.1 Synthesis, Properties, Surface Functionalization, and Applications of Nanoparticles -- 2.1.1 Magnetic Nanoparticles (MNPs) | |
| 505 | 8 | |a 2.1.1.1 Synthesis and Properties2.1.1.2 Surface Functionalization -- 2.1.1.3 Applications -- 2.1.1.3.1 Delivery of siRNA/DNA -- 2.1.1.3.2 Delivery of Drugs -- 2.1.1.3.3 MR Imaging -- 2.1.1.3.4 Hyperthermia -- 2.1.2 Gold Nanoparticles (GNPs) -- 2.1.2.1 Synthesis and Properties -- 2.1.2.2 Surface Functionalization -- 2.1.2.3 Applications -- 2.1.2.3.1 Delivery of siRNA/DNA -- 2.1.2.3.2 Delivery of Drugs -- 2.1.2.3.3 Plasmonic Photothermal Therapy (PPTT) -- 2.1.2.3.4 Photodynamic Therapy (PDT) -- 2.1.3 Core-Shell Nanoparticles (CSNPs) | |
| 505 | 8 | |a 2.1.3.1 Design of Core-Shell Nanomaterials2.1.3.2 Fabrication Techniques of Core-Shell Nanomaterials -- 2.1.3.2.1 Core Materials -- 2.1.3.2.2 Shell Fabrication -- 2.1.3.2.2.1 Metal-Oxide Shell -- 2.1.3.2.2.2 Noble Metal Shells -- 2.1.3.2.2.3 Dense Shells -- 2.1.3.2.2.4 Mesoporous Shells -- 2.1.3.3 Characterization Techniques for Core-Shell Nanoparticles [141] -- 2.1.3.4 Applications of Core-Shell Nanoparticles -- 2.1.3.4.1 Biomedical Applications -- 2.1.3.4.1.1 Drug Targeting and Delivery -- 2.1.3.4.1.2 Bioimaging -- 2.1.3.4.1.3 Sensors | |
| 500 | |a ""2.1.3.4.2 Catalytic Applications"" | ||
| 504 | |a Includes bibliographical references. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles. | ||
| 650 | 0 | |a Nanoparticles. |0 http://id.loc.gov/authorities/subjects/sh85089689 | |
| 650 | 0 | |a Nanomedicine. |0 http://id.loc.gov/authorities/subjects/sh2007008651 | |
| 650 | 0 | |a Biomedical engineering. |0 http://id.loc.gov/authorities/subjects/sh85014237 | |
| 650 | 7 | |a TECHNOLOGY & ENGINEERING |x Engineering (General) |2 bisacsh | |
| 650 | 7 | |a TECHNOLOGY & ENGINEERING |x Reference. |2 bisacsh | |
| 650 | 7 | |a Biomedical engineering. |2 fast |0 (OCoLC)fst00832568 | |
| 650 | 7 | |a Nanomedicine. |2 fast |0 (OCoLC)fst01744350 | |
| 650 | 7 | |a Nanoparticles. |2 fast |0 (OCoLC)fst01032624 | |
| 655 | 4 | |a Electronic books. | |
| 776 | 0 | 8 | |i Print version: |a Manisekaran, Ravichandran. |t Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics. |d Cham : Springer International Publishing, ©2017 |z 9783319676081 |
| 830 | 0 | |a Springer theses. |0 http://id.loc.gov/authorities/names/no2010186160 | |
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| 928 | |t Library of Congress classification |a RS201.N35 |l Online |c UC-FullText |u https://link.springer.com/10.1007/978-3-319-67609-8 |z Springer Nature |g ebooks |i 12549417 | ||