Advancing disease modeling in animal-based research in support of precision medicine : proceedings of a workshop /

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Bibliographic Details
Author / Creator:Forstag, Erin Hammers, rapporteur.
Imprint:Washington, DC : The Nationeal Academies Press, [2018]
©2018
Description:1 online resource (xiii, 122 pages) : color illustrations
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11655414
Hidden Bibliographic Details
Other authors / contributors:Anestidou, Lida, 1965- rapporteur.
Institute for Laboratory Animal Research (U.S.). Roundtable on Science and Welfare in Laboratory Animal Use, issuing body.
Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine (Workshop) (2017 : Washington, D.C.), author.
ISBN:9780309471190
0309471192
9780309471176
0309471176
9780309471169
0309471168
Notes:Includes bibliographical references (pages 90-94).
Online resource; title from PDF title page (National Academies Press, viewed June 4, 2018).
Summary:"Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.
Other form:Print version: Forstag, Erin Hammers. Advancing disease modeling in animal-based research in support of precision medicine : proceedings of a Workshop. Washington, D.C. : National Academies Press, ©2018 9780309471169
Standard no.:10.17226/25002

MARC

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245 1 0 |a Advancing disease modeling in animal-based research in support of precision medicine :  |b proceedings of a workshop /  |c Erin Hammers Forstag and Lida Anestidou, rapporteurs ; Roundtable on Science and Welfare in Laboratory Animal Use, Institute for Laboratory Animal Research, Division of Earth and Life Studies, the National Academies of Sciences, Engineering, Medicine. 
264 1 |a Washington, DC :  |b The Nationeal Academies Press,  |c [2018] 
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505 0 |a Introduction to precision medicine and animal models -- Existing precision medicine initiatives -- The promise and perils of animal models -- Reproducibility and predictivity -- In vitro alternatives to animal models -- Assessing safety and toxicology -- Patient perspectives -- Reflections on the workshop -- References. 
520 |a "Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop"--Publisher's description. 
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