PET/MRI in oncology : current clinical applications /

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Bibliographic Details
Imprint:Cham, Switzerland : Springer, [2018]
Description:1 online resource : illustrations (some color)
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11663971
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Other authors / contributors:Iagaru, Andrei, editor.
Hope, Thomas (Thomas A.), editor.
Veit-Haibach, Patrick, editor.
ISBN:9783319685175
3319685171
9783319685168
3319685163
Digital file characteristics:text file
PDF
Notes:Includes bibliographical references.
Vendor-supplied metadata.
Summary:In this book, experts from premier institutions across the world with extensive experience in the field clearly and succinctly describe the current and anticipated uses of PET/MRI in oncology. The book also includes detailed presentations of the MRI and PET technologies as they apply to the combined PET/MRI scanners. The applications of PET/MRI in a wide range of oncological settings are well documented, highlighting characteristic findings, advantages of this dual-modality technique, and pitfalls. Whole-body PET/MRI applications and pediatric oncology are discussed separately. In addition, information is provided on PET technology designs and MR hardware for PET/MRI, MR pulse sequences and contrast agents, attenuation and motion correction, the reliability of standardized uptake value measurements, and safety considerations. The balanced presentation of clinical topics and technical aspects will ensure that the book is of wide appeal. It will serve as a reference for specialists in nuclear medicine and radiology and oncologists and will also be of interest for residents in these fields and technologists.
Other form:Print version: PET/MRI in oncology. Cham, Switzerland : Springer, [2018] 3319685163 9783319685168
Standard no.:10.1007/978-3-319-68517-5
Table of Contents:
  • Intro; Foreword; Contents; About the Editor; 1: PET System Technology Designs for Achieving Simultaneous PET/MRI; 1.1 Introduction to MRI-Compatible PET System Technology; 1.2 Electromagnetic Interference; 1.2.1 Magnetic Susceptibility; 1.2.2 Shielding Effectiveness; 1.2.3 Eddy Current; 1.2.4 Annihilation Photon Attenuation; 1.3 Signal Generation and  Processing in PET; 1.3.1 Scintillators; 1.3.2 Photodetectors; 1.3.2.1 Photomultiplier Tubes; 1.3.2.2 Avalanche Photodiodes; 1.3.2.3 Silicon Photomultiplier; 1.3.3 Readout Electronics.
  • 1.4 Overview of  PET System Designs for PET/MRI1.4.1 Preclinical PET/MRI; 1.4.2 Commercial Clinical Integrated PET/MRI Systems; 1.4.2.1 Siemens BrainPET and  Biograph mMR; 1.4.2.2 GE SIGNA PET/MR; 1.4.3 Clinical PET Insert Systems for PET/MRI; 1.5 Summary and  Conclusion; References; 2: MR Pulse Sequences for PET/MRI; 2.1 Introduction; 2.2 Standard MR Pulse Sequences; 2.3 General Considerations; 2.3.1 System Limitations; 2.3.2 Whole-Body Imaging; 2.3.3 MR Attenuation Correction; 2.3.4 Fat/Water Imaging; 2.3.5 Bone Imaging; 2.3.6 Diffusion-Weighted Imaging.
  • 2.3.7 Whole-Body Diffusion-Weighted Imaging2.3.8 Lung Imaging; References; 3: MRI Contrast Agents; 3.1 Gadolinium-Based Contrast Agents (GBCAs); 3.1.1 Extracellular Contrast Agents; 3.1.2 Hepatobiliary Contrast Agents; 3.1.3 Blood Pool Contrast Agents; 3.1.4 Safety Concerns; 3.1.5 Safety Concerns: Nephrogenic Systemic Fibrosis; 3.1.6 Safety Concerns: Brain Deposition of  Gadolinium; 3.1.7 Safety Concerns: Allergic Reactions; 3.1.8 Safety Concerns: Overview; 3.2 Superparamagnetic Iron Oxides; 3.2.1 Ferumoxytol; 3.2.2 Safety Concerns: Anaphylaxis.
  • 3.3 MR Contrast Agents in Development3.3.1 Hyperpolarized MRI; References; 4: PET/MRI: Attenuation Correction; 4.1 Introduction; 4.2 Attenuation Correction; 4.3 Attenuation Correction in PET/MRI; 4.4 Segmentation-Based MRAC; 4.5 Bone Attenuation; 4.6 Truncation Correction; 4.6.1 PET Segmentation; 4.6.2 Joint Estimation of  Emission and  Transmission; 4.7 Hardware Correction; 4.8 Unsolved Issues; 4.8.1 Metal Artifacts; 4.8.2 Motion Artifacts; 4.8.3 Contrast; 4.8.4 Other Radiopharmaceuticals; 4.8.5 Phantoms; References; 5: PET/MRI: Motion Correction; 5.1 Introduction.
  • 5.2 MR-Based Motion Characterization5.2.1 Head Motion; 5.2.2 Respiratory Motion; 5.2.3 Cardiac Motion; 5.2.4 Dual Respiratory and  Cardiac Motion; 5.2.5 Bulk Motion; 5.3 PET Data Motion Compensation Algorithms; 5.3.1 Before Image Reconstruction; 5.3.2 During Image Reconstruction; 5.3.3 After Image Reconstruction; 5.4 Performance Evaluation of  MR-Based PET Motion Correction; 5.4.1 Methods; 5.4.1.1 Head Motion; 5.4.1.2 Respiratory Motion; 5.4.1.3 Cardiac Motion; 5.4.1.4 Dual Cardiac and  Respiratory Motion; 5.5 Beyond Proof-of-Principle Studies; References.