HIV vaccines and cure : the path towards finding an effective cure and vaccine /

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Bibliographic Details
Imprint:Singapore : Springer, [2018]
©2018
Description:1 online resource (xv, 318 pages) : illustrations (chiefly color)
Language:English
Series:Advances in experimental medicine and biology, 2214-8019 ; volume 1075
Advances in experimental medicine and biology ; v. 1075.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11678804
Hidden Bibliographic Details
Other authors / contributors:Zhang, Linqi, editor.
Lewin, Sharon, editor.
ISBN:9789811304842
981130484X
9789811304835
9811304831
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Online resource; title from electronic title page (SpringerLink, viewed September 14, 2018).
Summary:"This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry"--Publisher's description.
Other form:Print versvion: HIV vaccines and cure. Singapore : Springer, [2018] 9789811304835
Standard no.:10.1007/978-981-13-0484-2

MARC

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245 0 0 |a HIV vaccines and cure :  |b the path towards finding an effective cure and vaccine /  |c Linqi Zhang, Sharon R. Lewin, editors. 
264 1 |a Singapore :  |b Springer,  |c [2018] 
264 4 |c ©2018 
300 |a 1 online resource (xv, 318 pages) :  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Advances in experimental medicine and biology,  |x 2214-8019 ;  |v volume 1075 
504 |a Includes bibliographical references. 
505 0 |a HIV vaccines. HIV vaccine efficacy trials: RV144 and beyond / Elizabeth Heger, Alexandra Schuetz, Sandhya Vasan -- HIV T-cell vaccines / Beatriz Mothe, Christian Brander -- HIV broadly neutralizing antibodies: VRC01 and beyond / Xueling Wu -- Structural features of broadly neutralizing antibodies and rational design of vaccine / Tongqing Zhou, Kai Xu -- Monkey models and HIV vaccine research / Zhiwei Chen -- Treatment of HIV for the prevention of transmission in discordant couples and at the population level / M. Kumi Smith, Britta L. Jewell, Timothy B. Hallett, Myron S. Cohen -- HIV cure. HIV persistence on antiretroviral therapy and barriers to a cure / Julia Marsh Sung, David M. Margolis -- The molecular biology of HIV latency / Georges Khoury, Gilles Darcis, Michelle Y. Lee, Sophie Bouchat, Benoit Van Driessche, Damian F.J. Purcell [and others] -- Cellular determinants of HIV persistence on antiretroviral therapy / Anastassia Mikhailova, Jose Carlos Valle-Casuso, Asier Sáez-Cirión -- In vitro and in vivo models of HIV latency / James B. Whitney, R. Brad Jones -- Measuring HIV persistence on antiretroviral therapy / Bethany A. Horsburgh, Sarah Palmer -- Clinical interventions in HIV cure research / Thomas Aagaard Rasmussen, Ole S. Søgaard. 
520 |a "This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry"--Publisher's description. 
588 0 |a Online resource; title from electronic title page (SpringerLink, viewed September 14, 2018). 
650 0 |a AIDS vaccines.  |0 http://id.loc.gov/authorities/subjects/sh88007929 
650 0 |a Antiretroviral agents.  |0 http://id.loc.gov/authorities/subjects/sh2003006231 
650 0 |a HIV infections  |x Chemotherapy. 
650 1 2 |a AIDS Vaccines. 
650 1 2 |a HIV Infections  |x drug therapy. 
650 2 2 |a Acquired Immunodeficiency Syndrome  |x prevention & control. 
650 2 2 |a Anti-Retroviral Agents. 
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650 7 |a Animal pathology & diseases.  |2 bicssc 
650 7 |a Medical microbiology & virology.  |2 bicssc 
650 7 |a AIDS vaccines.  |2 fast  |0 (OCoLC)fst00794025 
650 7 |a Antiretroviral agents.  |2 fast  |0 (OCoLC)fst00810765 
650 7 |a HIV infections  |x Chemotherapy.  |2 fast  |0 (OCoLC)fst00949874 
655 4 |a Electronic books. 
700 1 |a Zhang, Linqi,  |e editor. 
700 1 |a Lewin, Sharon,  |e editor.  |0 http://id.loc.gov/authorities/names/n97845428 
776 0 8 |i Print versvion:  |t HIV vaccines and cure.  |d Singapore : Springer, [2018]  |z 9789811304835  |w (DLC) 2018948148  |w (OCoLC)1030907284 
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