Hidden Bibliographic Details
| Other authors / contributors: | Castria, Tiago Biachi de, editor.
Guindalini, Rogo Santa Cruz, editor.
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| ISBN: | 9783319952345
331995234X
9783319952352
3319952358
9783319952338
3319952331
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| Digital file characteristics: | text file PDF
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| Notes: | Includes index.
Online resource; title from PDF title page (SpringerLink, viewed September 18, 2018).
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| Summary: | We live in an era of personalized medicine and the knowledge about pathophysiology of diffuse gastric cancer has had many advances. Thus, the role of this work is to clarify what is new from diagnosis to treatment of this disease in order to treat patients in the most tailored manner as possible. Almost all phase III trials in gastric cancer have been performed without taking in consideration histologic subtypes, i.e. they have disregarded the differences between diffuse gastric cancer and general gastric cancer. However, the clinical practice reveals that diffuse gastric cancer is a completely distinct disease, with an aggressive course and generally worse prognosis. The loss of cohesion between tumor cells due to the loss of E-cadherin synthesis is the critical point on the oncogenesis of diffuse gastric cancer and is at the root of its marked heredity. This book intends to give special attention to Diffuse Gastric Cancer as a particular oncological entity, differentiating it from general gastric cancer, exploring and discussing all its peculiarities, and addressing the basic aspects (pathology and genetics) along with the most recent therapeutic alternatives for this condition.
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| Other form: | Print version: Diffuse gastric cancer. Cham, Switzerland : Springer, 2018 3319952331 9783319952338
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| Standard no.: | 10.1007/978-3-319-95234-5
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