Diffuse gastric cancer /
Saved in:
Imprint: | Cham, Switzerland : Springer, 2018. |
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Description: | 1 online resource |
Language: | English |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11705960 |
Table of Contents:
- Intro; Acknowledgments; Contents; Contributors; Chapter 1: Introduction; References; Chapter 2: Epidemiology; Incidence andMortality; Diffuse-Type Gastric Carcinoma; Risk Factors; Environmental Factors; Helicobacter pylori; Smoking; Dietary Habits andNitroso Compounds; Obesity; Epstein-Barr Virus; Host Factors; Blood Group; CDH1 Gene; Differences Between Intestinal andDiffuse Subtypes; Age ofOccurrence; Location ofTumors; H. pylori Infection; Stomach Microbiome; Interfering withtheDiffuse-Type Gastric Cancer Burden; References; Chapter 3: The Role ofEndoscopy; Preneoplastic Changes
- DiagnosisEndoscopic Classifications; Biopsy; Endoscopic Ultrasonography Staging; Treatment; Early Gastric Cancer; Advanced Gastric Cancer; Hereditary Screening; References; Chapter 4: Pathology andMolecular Biology; Molecular Biology ofGastric Cancer; Genomic Alterations; Epigenetics; DNA Methylation; Histone Alterations; MicroRNA; Gene andProtein Expression; Pathways; E-Cadherin andCell Adhesion; E-Cadherin andtheWnt/Beta-Catenin Signaling Pathway; E-Cadherin andEpithelial-to-Mesenchymal Transition; E-Cadherin Expression andFunction; Germline andSomatic Mutations inCDH1 Gene
- Transcriptional Regulation ofE-Cadherin ExpressionPosttranslational Regulation ofE-Cadherin Expression; RHOA Pathway; Survival According toMolecular Subtypes; References; Chapter 5: Genetic Predisposition andHereditary Syndromes; Introduction; Genetic Counseling andMutation Analysis; Screening andSurveillance; Endoscopic Screening forGastric Cancer; Breast Cancer Surveillance; Gastrectomy andMastectomy; Prophylactic Gastrectomy: Indications forandTiming ofSurgery; Prophylactic Mastectomy; References; Chapter 6: The Role ofSurgery; Management of Primary Tumor Site; Lymphadenectomy
- Surgical AccessLaparoscopy; Prophylactic Gastrectomy inHereditary Diffuse Gastric Cancer; Diffuse Gastric Cancer inYoung Patients; Diffuse Gastric Cancer andPrognosis; Conclusions; References; Chapter 7: The Role ofRadiation Therapy; INT 0116; ARTIST Trial; SEER Data; Meta-analysis; Patterns ofRelapse; Ongoing Trials; Radiation Therapy Recommendations; References; Chapter 8: The Role ofChemotherapy; Introduction; Curative Chemotherapy forDiffuse Gastric Cancer; Clinical Trials ofCurative Chemotherapy andDiffuse Gastric Cancer; Palliative Chemotherapy forDiffuse Gastric Cancer
- Retrospective AnalysesRandomized Clinical Trials; Second-Line Systemic Treatment; Target Therapy; Chemotherapy andMolecular Profile ofDiffuse Gastric Cancer; Imunotherapy; Conclusion; References; Index