Glycobiophysics /

Glycobiophysics /

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Bibliographic Details
Imprint:Singapore : Springer, [2018]
©2018
Description:1 online resource (xiii, 277 pages) : illustrations (chiefly color)
Language:English
Series:Advances in experimental medicine and biology, 2214-8019 ; volume 1104
Advances in experimental medicine and biology ; v. 1104.
Subject:
Glycomics.
Biophysics.
Polysaccharides -- chemistry.
Glycomics -- methods.
Biophysics -- methods.
Glycoproteins -- chemistry.
Biophysics.
Glycomics.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11737738
Hidden Bibliographic Details
Other authors / contributors:Yamaguchi, Yoshiki, editor.
Kato, Koichi (Professor), editor.
ISBN:9789811321580
9811321582
9789811321573
9811321574
Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
Online resource; title from electronic title page (SpringerLink, viewed December 10, 2018).
Summary:"This book presents state of the art biophysical approaches to issues in glycobiology that have cutting-edge applications. Despite the importance of glycosylation, the complexity, heterogeneity, and flexibility of the glycans have inhibited their study. Each chapter in this book explains very recent significant advances in biophysical approaches through the use of techniques such as NMR spectroscopy, mass spectrometry, single-molecule imaging, X-ray crystallography, high-speed atomic force microscopy, and computational simulation and their integrative application. Concrete examples are provided of the value of these techniques in addressing key problems in the field. In addition, significant functional glycobiological issues are considered. For example, glycolipids can form dynamic clusters on cell membranes and provide platforms for molecules involved in cell recognition and subsequent signal transduction. The detailed delineation of these molecular systems is discussed, revealing their structural complexity and ability to assemble transiently. This timely book will be of value for graduate students and postdocs interested in frontier topics in glycoscience and also for senior bio-researchers in academic and industrial fields"--Publisher's description.
Other form:Print version: Glycobiophysics. Singapore: Springer, [2018] 9789811321573
Standard no.:10.1007/978-981-13-2158-0
Table of Contents:
  • Effects of N-glycans on glycoprotein folding and protein dynamics / Yoko Amazaki, Hien Minh Nguyen, Ryo Okamoto, Yuta Maki, Yasuhiro Kajihara
  • Synthesis of glycosylated metal complexes for probing carbohydrate-carbohydrate interactions / Teruaki Hasegawa
  • Unraveling of lipid raft organization in cell plasma membranes by single-molecule imaging of ganglioside probes / Kenichi G.N. Suzuki, Hiromune Ando, Naoko Komura, Takahiro Fujiwara, Makoto Kiso, Akihiro Kusumi
  • MALDI mass spectrometry imaging of N-linked glycans in tissues / Richard R. Drake, Connor A. West, Anand S. Mehta, Peggi M. Angel
  • Isomeric separation and characterisation of glycoconjugates / Kathirvel Alagesan, Arun Everest-Dass, Daniel Kolarich
  • Synchrotron-radiation vacuum-ultraviolet circular-dichroism spectroscopy for characterizing the structure of saccharides / Koichi Matsuo, Kunihiko Gekko
  • Biophysical analyses for probing glycan-protein interactions / Masamichi Nagae, Yoshiki Yamaguchi
  • Structural aspects of ER glycoprotein quality-control system mediated by glucose tagging / Tadashi Satoh, Koichi Kato
  • Structural basis of protein Asn-glycosylation by oligosaccharyltransferases / Daisuke Kohda
  • Visualization of functional structure and kinetic dynamics of cellulases / Akihiko Nakamura, Ryota Iino
  • Structure and dynamics of immunoglobulin G glycoproteins / Hirokazu Yagi, Saeko Yanaka, Koichi Kato
  • Biophysical approaches to solve the structures of the complex glycan shield of chloroviruses / Cristina De Castro, Garry A. Duncan, Domenico Garozzo, Antonio Molinaro, Luisa Sturiale, Michela Tonetti [and others]
  • Quantifying weak glycan-protein interactions using a biolayer interferometry competition assay: applications to ECL Lectin and X-31 influenza hemagglutinin / Ye Ji, Robert J. Woods.

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