Chaperokine activity of heat shock proteins /

Chaperokine activity of heat shock proteins /

Saved in:

Bibliographic Details
Imprint:	Cham, Switzerland : Springer, 2019.
Description:	1 online resource (ix, 320 pages) : illustrations (some color)
Language:	English
Series:	Heat shock proteins, 1877-1246 ; volume 16 Heat shock proteins (Series) ; v. 16.
Subject:	Heat shock proteins. Molecular chaperones. Heat shock proteins. Molecular chaperones. Electronic books.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11792348

Hidden Bibliographic Details
Other authors / contributors:	Asea, Alexzander A. A., editor. Kaur, Punit, editor.
ISBN:	9783030022549 3030022544 9783030022532 3030022536 9783030022556 3030022552
Digital file characteristics:	text file PDF
Notes:	Includes index. Includes bibliographical references and index. Online resource; title from PDF title page (SpringerLink, viewed February 7, 2019).
Summary:	Chaperokine is a term that describes the unique function of extracellular heat shock protein (eHsp) as both chaperone and cytokine. The cellular consequence of binding and signaling of eHsp is the stimulation of a potent and long lasting immune response. eHsp induces a plethora of immune responses including the release of bioactive mediators such as cytokines, chemokines, nitric oxide, apotogenic mediators, stimulation of the innate and adaptive immune response, migration and maturation of dendritic cells (DC) and the enhancement of natural killer cell-mediated cellular cytotoxicity. This edited book provides the most comprehensive review of contemporary knowledge of the chaperokine activity of heat shock proteins (HSP) in biology and medicine. Using an integrative approach to understanding the chaperokine activity of HSP, the contributors provide an overview of novel mechanisms, signal transduction pathways and a concise understanding of how the principles of the chaperokine activity of HSP has been harnessed for therapeutic gain. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present cutting-edge research activities and importantly, the future direction of chaperokine research. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychology, Human Physiology, Zoology, Botany, Biotechnology, Molecular Medicine, Infectious Disease, Pathology and Pharmaceutical Sciences, as well as for researchers involved in Drug Discovery.
Other form:	Print version: 3030022536 9783030022532
Standard no.:	10.1007/978-3-030-02254-9 10.1007/978-3-030-02

Description
Summary:	<p>Chaperokine, is a term that describes the unique function of extracellular heat shock protein (eHsp) as both chaperone and cytokine. The cellular consequence of binding and signaling of eHsp is the stimulation of a potent and long lasting immune response. eHsp induces a plethora of immune responses including the release of bioactive mediators like cytokines, chemokines, nitric oxide, apotogenic mediator, stimulation of the innate and adaptive immune response, migration and maturation of dendritic cells (DC) and the enhancement of natural killer cell-mediated cellular cytotoxicity.</p> <p>The book Chaperokine Activity of Heat Shock Proteins provides the most comprehensive review on contemporary knowledge on the chaperokine activity of heat shock proteins (HSP) in biology and medicine. Using an integrative approach to understanding the chaperokine activity of HSP, the contributors provide a synopsis of novel mechanisms, signal transduction pathways and how the principlesof the chaperokine activity of HSP has been harnessed for therapeutic gain.</p> <p>To enhance the ease of reading and comprehension this book has been subdivided into various section, including; Section I, reviews current progress on our understanding of Immunological and Inflammatory Responses; Section II, evaluates the role of Physiological Responses and Section III, focuses the reader on the Therapeutic Approach. </p> Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychologists, Human Physiology, Zoologists, Botanists, Biotechnology, Molecular Medicine, Infectious Diseases Experts, Pathologists, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Item Description:	Includes index.
Physical Description:	1 online resource (ix, 320 pages) : illustrations (some color)
Bibliography:	Includes bibliographical references and index.
ISBN:	9783030022549 3030022544 9783030022532 3030022536 9783030022556 3030022552
ISSN:	1877-1246 ;