Adeno-associated virus vectors : design and delivery /

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Bibliographic Details
Imprint:New York, NY : Humana Press : Springer, [2019]
©2019
Description:1 online resource (xii, 426 pages) : illustrations (some color)
Language:English
Series:Methods in molecular biology, 1940-6029 ; volume 1950
Methods in molecular biology (Clifton, N.J.) ; v. 1950.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11792572
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Other authors / contributors:Castle, Michael J., editor.
ISBN:9781493991396
1493991396
9781493991389
1493991388
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (SpringerLink, viewed February 19, 2019).
Summary:This volume provides a complete and timely guide to the use of adeno-associated virus (AAV) vectors for genetic manipulation of mammalian tissues. Beginning with methods for the design and characterization of AAV vectors, the book continues with protocols for AAV delivery to various components of the central nervous system, to a number of sensory systems, and to a broad range of other tissues. Novel techniques such as ultrasound-targeted delivery to the brain, subpial delivery to the spinal cord, and subILM delivery to the retina are accompanied by chapters that provide an overview and comparison of current methods for AAV delivery to tissues such as brain, heart, liver, and lung. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible step-by-step laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Other form:Print version: Adeno-associated virus vectors. New York : Springer, [2019] 9781493991389

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