Clinical immunology : principles and practice /
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| Edition: | Fifth edition. |
|---|---|
| Imprint: | [St. Louis, Mo.] : Elsevier, [2019] ©2019 |
| Description: | 1 online resource (xviii, 1318 pages) : illustrations (chiefly color) |
| Language: | English |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11937914 |
Table of Contents:
- Section 1: Principles of immune response. The human immune response
- Organization of the immune system
- Innate immunity
- Antigen receptor genes, gene products, and co-receptors
- The major histocompatibility complex
- Antigens and antigen presentation
- B-cell development and differentiation
- T-cell development
- Cytokines and cytokine receptors
- Chemokines and chemokine receptors
- Lymphocyte adhesion and trafficking
- T-cell activation and tolerance
- Regulated cell death
- The microbiota in immunity and inflammation
- Section 2: Host defense mechanisms and inflammation. Immunoglobulin function
- Helper T-cell subsets and control of the inflammatory response
- Cytotoxic T lymphocytes and natural killer cells
- Regulatory immune cells
- Host defenses in the skin
- Host defenses at mucosal surfaces
- Complement in host deficiencies and diseases
- Phagocyte deficiencies
- Mast cells, basophils, and mastocytosis
- Eosinophils and eosinophilia
- Section 3: Host defenses to infectious agents. Host defenses to viruses
- Host defenses to intracellular bacteria
- Host defenses to extracellular bacteria
- Host defenses to spirochetes
- Host defenses to fungi
- Host defenses to protozoa
- Host defenses to helminths
- Section 4: Immunologic deficiencies. Approach to the evaluation of the immunodeficient patient
- Human genomics in immunology
- Primary antibody deficiencies
- Primary T-cell immunodeficiencies
- Immunodeficiencies at the interface of innate and adaptive immunity
- Infections in the immunocompromised host
- Immune deficiencies at the extremes of age
- HIV infection and acquired immunodeficiency syndrome
- Autoantibody mediated phenocopies of primary immunodeficiency diseases
- Section 5: Allergic diseases. Immunological mechanisms of airway diseases and pathways to therapy
- Urticaria, angioedema, and anaphylaxis
- Allergic reactions to stinging and biting insects
- Atopic and contact dermatitis
- Food allergy
- Eosinophil-associated gastrointestinal disorders
- Allergic disorders of the eye
- Drug hypersensitivity
- Occupational respiratory allergies
- Section 6: Systemic immune diseases. Mechanisms of autoimmunity
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Juvenile idiopathic arthritis
- Sjögren's syndrome
- Scleroderma-systemic sclerosis
- Inflammatory muscle diseases
- Spondyloarthritis
- Small and medium vessel primary vasculitis
- Large-vessel vasculitides
- Systemic autoinflammatory syndromes
- Antiphospholipid syndrome
- Section 7: Organ-specific inflammatory disease. Immunohematologic disorders
- Bullous diseases of the skin and mucous membranes
- Immunology of psoriasis
- Myasthenia gravis
- Multiple sclerosis
- Autoimmune peripheral neuropathies
- Immunologic renal diseases
- Inflammation and atherothrombosis
- Autoimmune thyroid diseases
- Diabetes and related autoimmune diseases
- Immunologic lung diseases
- Sarcoidosis
- Immunologic ocular disease
- Immunologic diseases of the gastrointestinal tract
- Inflammatory hepatobiliary diseases
- Section 8: Immunology of neoplasia. Tumor immunotherapy
- Lymphoid leukemias
- Lymphomas
- Monoclonal gammopathies
- Section 9: Transplantation. Concepts and challenges in organ transplantation: rejection, immunosuppression, and tolerance
- Immune reconstitution therapy for immunodeficiency
- Hematopoietic stem cell transplantation for malignant diseases
- Section 10: Prevention and therapy of immunologic diseases. Immunoglobulin therapy: replacement and immunomodulation
- Gene therapy
- Glucocorticoids
- Immunomodulating pharmaceuticals
- Protein kinase antagonists as therapeutic agents for immunological and inflammatory disorders
- Biological modifiers of inflammation
- Vaccines
- Immunotherapy of allergic disease
- Section 11: Diagnostic immunology. Flow cytometry
- Assessment of functional immune responses
- Assessment of neutrophil function
- Assessment of human allergic diseases
- Molecular methods
- Appendices. Selected CD molecules and their characteristics
- Laboratory reference values
- Vaccine schedules.