Pot, atom, and step economy (PASE) synthesis /

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Bibliographic Details
Author / Creator:	Zhang, Wei, author.
Imprint:	Cham : Springer, [2019]
Description:	1 online resource (55 pages)
Language:	English
Series:	SpringerBriefs in molecular science, 2191-5415 Green chemistry for sustainability, 2452-185X SpringerBriefs in molecular science. SpringerBriefs in molecular science. Green chemistry for sustainability.
Subject:	Organic compounds -- Synthesis. Green chemistry. Chemical reactions. Chemical reactions. Green chemistry. Organic compounds -- Synthesis.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11938180

Hidden Bibliographic Details
Other authors / contributors:	Yi, Wen-Bin, author.
ISBN:	3030225968 9783030225940 3030225941 9783030225957 303022595X 9783030225964
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references. Print version record.
Summary:	This book emphasizes the atom economy aspect of multicomponent reactions. It describes how this methodology has been applied to several named reactions. Among the "twelve principles of green chemistry", atom economy addresses 'synthetic efficiency. A multicomponent reaction can be defined as an energy, cost, and time efficient method for organic synthesis. Instead of making one or two bonds in a chemical transformation, multicomponent reactions generate several chemical bonds in a single operation. This book presents a series of detailed reaction mechanisms that beautifully illustrate this principle. Multicomponent reactions are widely applied to the preparation of complex and diverse molecular structures in academic and industrial research laboratories. As such, this book is targeted at researchers involved in green organic chemistry.
Other form:	Print version: Zhang, Wei. Pot, Atom, and Step Economy (PASE) Synthesis. Cham : Springer, ©2019 9783030225940
Standard no.:	10.1007/978-3-030-22596-4

Table of Contents:

Intro; Preface; Contents; Abbreviations; 1 Introduction to PASE Synthesis; References; 2 One-Pot Reactions; 2.1 Introduction; 2.2 One-Pot Non-catalytic Reactions; 2.3 One-Pot Catalytic Reactions; 2.4 One-Pot Cycloaddition Reactions; References; 3 Cascade Reactions; 3.1 Introduction; 3.2 Cascade Ionic Reactions; 3.3 Cascade Transition Metal-Catalyzed Reactions; 3.4 Cascade Pericyclic Reactions; 3.5 Cascade Radical Reactions; References; 4 Multicomponent Reactions (MCRs); 4.1 Introduction; 4.2 Direct MCRs; 4.3 High-Order MCRs; 4.4 MCRs Followed by Post-condensation Modifications
4.5 Consecutive MCRsReferences; 5 Applications of PASE Synthesis; 5.1 Introduction; 5.2 PASE Synthesis in Medicinal Chemistry; 5.3 PASE Synthesis in Natural Product Synthesis; References; 6 Conclusive Remarks

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