Hidden Bibliographic Details
| ISBN: | 9783030294731
3030294730
9783030294724
3030294722
9783030294724
9783030294748
3030294749
9783030294755
3030294757
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| Digital file characteristics: | text file PDF
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| Notes: | "Doctoral thesis accepted by the University of Campinas, Campinas, Brazil."
Includes bibliographical references.
Online resource; title from PDF title page (SpringerLink, viewed October 31, 2019).
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| Summary: | This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.
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| Other form: | Printed edition: 9783030294724
Printed edition: 9783030294748
Printed edition: 9783030294755
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| Standard no.: | 10.1007/978-3-030-29473-1
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