Type I Interferon in Human Autoimmunity.

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Bibliographic Details
Author / Creator:Timothy B. Niewold.
Imprint:Frontiers Media SA 2015.
Description:1 electronic resource (87 pages)
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12328792
Hidden Bibliographic Details
Other uniform titles:Directory of open access books.
ISBN:9782889193400
2889193403
Notes:Access restricted to subscribing institutions.
English.
Summary:The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical mediator of human autoimmune disease. Type I interferons function as a bridge between the innate and adaptive immune systems, and as such play an important role in setting thresholds for response against self antigens. Many investigators have focused on the role type I interferons play in autoimmune disease. This fascinating and rapidly growing body of literature encompasses many different autoimmune diseases, including systemic lupus erythematosus, type I diabetes, multiple sclerosis, and others. In this Research Topic, we provide a comprehensive overview of the various roles type I interferons play in autoimmune diseases, with a focus on human immunology.

MARC

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653 |a Interferons 
653 |a systemic lupus erythematosus 
653 |a Multiple Sclerosis 
653 |a Sjogren's Syndrome 
653 |a systemic sclerosis 
653 |a autoimmune thyroid disease 
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