Hidden Bibliographic Details
| Other authors / contributors: | Bodmer, Rolf.
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| ISBN: | 9780080554389
0080554385
0444530142
9780444530141
9780444530141
1281071188
9781281071187
9786611071189
6611071180
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| Notes: | Includes bibliographical references and index.
Restrictions unspecified
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212
English.
digitized 2010 HathiTrust Digital Library committed to preserve
Print version record.
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| Summary: | In 1993, Rolf Bodmer described a gene he named tinman that was required for the formation of the dorsal aorta of the fly. Flies without a functional tinman gene had no heart. Quickly, mammalian counterparts of the tinman gene were identified and found to be expressed by early cardiomyogenic precursors and by cardiomyocytes throughout heart development. Since then, significant progress has been made in the understanding of molecular and genetic determinants of heart formation. An ever growing number of genes have been identified that are required for cardiogenesis, as evidenced by severe abnormalities in cardiac development produced by inactivation in the mouse or inhibition of gene function in other model organisms. Cardiovascular Development covers some of the latest research in the study of heart formation. Volume Editor Rolf Bodmer has assembled a world-class list of contributors whose research uses a variety of animal models and whose findings are certain to enhance our understanding of this exciting field. * Ties together the development of heart morphology and conduction system * The latest developments in vertebrate and invertebrate genetic model systems * Technological advancements in cardiovascular science.
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| Other form: | Print version: Cardiovascular development. 1st ed. Amsterdam ; Boston : Elsevier, 2008
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