Glycan and glycosaminoglycans as clinical biomarkers and therapeutics. Part B /
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Imprint: | Cambridge : Academic Press, 2019. |
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Description: | 1 online resource |
Language: | English |
Series: | Progress in molecular biology and translational science ; volume 163 Progress in molecular biology and translational science ; v. 163. |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/12379405 |
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245 | 0 | 0 | |a Glycan and glycosaminoglycans as clinical biomarkers and therapeutics. |n Part B / |c edited by Lijuan Zhang. |
260 | |a Cambridge : |b Academic Press, |c 2019. | ||
300 | |a 1 online resource | ||
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490 | 1 | |a Progress in molecular biology and translational science ; |v volume 163 | |
520 | |a Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B, Volume 163 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include an Overview of Fugal Glycan-based Therapeutics, Heparin: An Essential Drug for Modern Medicine, Low Molecular Weight Heparins and Their Clinical Applications, The Clinical Use of Fondaparinux: A Synthetic Heparin Pentasaccharid, Heparinoids as Clinically Used Drugs, Marine Glycan-Derived Therapeutics in China, Efficacy of Heparinoid PSS in Treating Cardiovascular and other Diseases-30 Years Clinical Applications in China, and more. | ||
500 | |a Includes index. | ||
588 | 0 | |a Print version record. | |
505 | 0 | |a Front Cover; Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics -- Part B; Copyright; Contents; Contributors; Preface; Chapter One: Heparin: An essential drug for modern medicine; 1. Introduction; 2. Structure of heparin; 3. The mechanisms of the heparin; 4. Clinical studies of heparin; 4.1. Anti-coagulation activity of heparin; 4.2. Anti-cancer activity of heparin; 4.3. Heparin in inflammatory diseases; 4.4. Heparin in infectious disease; 4.5. Other diseases; 5. Concluding remarks; Acknowledgments; References | |
505 | 8 | |a Chapter Two: Low molecular weight heparins and their clinical applications1. Introduction; 2. Structure of LMWHs; 3. Clinical uses of LMWHs; 4. Update on the LMWHs under clinic trials and its potential applications; 4.1. Anti-tumor; 4.2. Anti-viral; 4.3. Anti-inflammation; 4.4. Anti-diabetes-associated complications; 4.5. Other applications; 5. Concluding remarks; Acknowledgments; References; Chapter Three: The clinical use of Fondaparinux: A synthetic heparin pentasaccharide; 1. Structure and mechanism of Fondaparinux; 2. Pharmacokinetics and pharmacodynamics of Fondaparinux | |
505 | 8 | |a 3. Clinical application of Fondaparinux3.1. Prophylaxis of VTE; 3.2. Prophylaxis of DVT; 3.3. Other clinical indications; 4. Concluding remarks; Acknowledgments; Conflict of interest; References; Chapter Four: Heparinoids Danaparoid and Sulodexide as clinically used drugs; 1. Heparin and heparinoids; 2. Heparin, low molecular weight heparin, Danaparoid and Sulodexide; 3. Clinical applications of Danaparoid; 3.1. Danaparoid in HIT; 3.2. Danaparoid in DVT; 3.3. Danaparoid in DIC; 4. Clinical applications of Sulodexide; 4.1. Anticoagulant and antithrombotic activity | |
505 | 8 | |a 4.2. Prevention of reperfusion injury4.3. Sulodexide in other diseases; 5. Concluding remarks; Acknowledgments; References; Chapter Five: Efficacy of heparinoid PSS in treating cardiovascular diseases and beyond-A review of 31 years clinical exp ... ; 1. Introduction; 2. Preparation, chemical structure, and clinical doses; 3. Clinical uses and efficacy; 4. Adverse reactions; 5. Pharmacodynamics; 6. Pharmacokinetics; 7. Future perspectives; Acknowledgment; Conflicts of interest; References; Chapter Six: Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies | |
505 | 8 | |a 1. Introduction2. Preparation and structure of fucoidan; 3. Pharmacology and mechanism of fucoidan; 3.1. Chronic renal failure (CRF); 3.2. Acute kidney injury (AKI); 3.3. Diabetic nephropathy (DN); 4. Clinical uses and efficacy of fucoidan; 5. Future perspectives; Acknowledgments; References; Chapter Seven: Marine glycan-derived therapeutics in China; 1. Introduction; 2. Fucoidan (Haikunshenxi capsules); 2.1. Chemical structure and preparation; 2.2. Pharmacological activities; 2.3. Clinical applications; 3. Chitin ester (PS916); 3.1. Pharmacological activities; 3.2. Pharmacokinetics | |
504 | |a Includes bibliographical references and index. | ||
650 | 0 | |a Glycomics. |0 http://id.loc.gov/authorities/subjects/sh2003010544 | |
650 | 0 | |a Glycoconjugates. |0 http://id.loc.gov/authorities/subjects/sh92001641 | |
650 | 0 | |a Biochemical markers. |0 http://id.loc.gov/authorities/subjects/sh85014122 | |
650 | 2 | |a Glycomics. | |
650 | 2 | |a Glycoconjugates. | |
650 | 2 | |a Biomarkers. | |
650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
650 | 7 | |a Biochemical markers. |2 fast |0 (OCoLC)fst00831950 | |
650 | 7 | |a Glycoconjugates. |2 fast |0 (OCoLC)fst00943768 | |
650 | 7 | |a Glycomics. |2 fast |0 (OCoLC)fst00943787 | |
655 | 4 | |a Electronic books. | |
700 | 1 | |a Zhang, Lijuan. |0 http://id.loc.gov/authorities/names/n2001089434 |1 http://viaf.org/viaf/249731669 | |
776 | 0 | 8 | |i Print version: |z 0128177403 |z 9780128177402 |w (OCoLC)1052874139 |
830 | 0 | |a Progress in molecular biology and translational science ; |v v. 163. |0 http://id.loc.gov/authorities/names/no2009049039 | |
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