Protein-ligand interactions and drug design /

Protein-ligand interactions and drug design /

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Bibliographic Details
Imprint:	New York, NY : Humana Press, [2021]
Description:	1 online resource (xv, 327 pages) : illustrations (some color)
Language:	English
Series:	Methods in molecular biology, 1064-3745 ; 2266 Springer protocols Methods in molecular biology (Clifton, N.J.) ; v. 2266. Springer protocols (Series)
Subject:	Drugs -- Computer-aided design. Proteins. Ligands (Biochemistry) Proteins Ligands (Biochemistry) Proteins Laboratory Manual Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/12543816

Hidden Bibliographic Details
Other authors / contributors:	Ballante, Flavio, editor.
ISBN:	9781071612095 1071612093 9781071612088 1071612085
Notes:	Includes bibliographical references and index. Online resource; title from PDF title page (SpringerLink, viewed April 16, 2021).
Summary:	This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition. Beginning with methods that allow for the exploration of specific areas of chemical space and the designing of virtual libraries, the volume continues with sections on methods based on docking, quantitative models, and molecular dynamics simulations, which are employed for ligand discovery or development, as well as methods exploiting an ensemble of protein structures for the identification of potential protein targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Protein-Ligand Interactions and Drug Design provides detailed practical procedures of solid computer-aided drug design methodologies employed to rationalize and optimize protein-ligand interactions, for experienced researchers and novices alike.
Other form:	Print version: 9781071612088
Standard no.:	10.1007/978-1-0716-1209-5

Description
Physical Description:	1 online resource (xv, 327 pages) : illustrations (some color)
Bibliography:	Includes bibliographical references and index.
ISBN:	9781071612095 1071612093 9781071612088 1071612085
ISSN:	1064-3745 ;