Bacterial membrane vesicles : biogenesis, functions and applications /
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Imprint: | Cham : Springer, ©2020. |
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Description: | 1 online resource (258 pages) |
Language: | English |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/12604631 |
Table of Contents:
- Intro
- Preface
- Contents
- Editors and Contributors
- Chapter 1: Introduction, History, and Discovery of Bacterial Membrane Vesicles
- 1.1 Introduction to Gram-Negative OMVs
- 1.1.1 The First Observations of OMVs
- 1.1.2 Advances in OMV Research
- 1.1.3 Outer Membrane Vesicles Research in the Last Decade
- 1.1.4 Biogenesis of OMVs
- 1.1.5 Outer Membrane Vesicles in Bacterial Communication
- 1.1.6 Outer Membrane Vesicles in Host-Pathogen Interactions
- 1.1.7 Distribution of OMVs in the Environment
- 1.2 Introduction to Gram-Positive MVs
- 1.2.1 Production and Biogenesis of Gram-Positive MVs
- 1.2.2 Contents of Gram-Positive MVs
- 1.2.3 Role of MVs in Inter-Bacterial Communication
- 1.2.4 Role of MVs in Host-Pathogen Interactions
- 1.3 Conclusions
- References
- Chapter 2: Biogenesis of Gram-Negative OMVs
- 2.1 Introduction
- 2.2 Modulation of Outer Membrane-Peptidoglycan Linkages
- 2.2.1 Braunś Lipoprotein (Lpp)
- 2.2.2 Outer Membrane Protein A (OmpA)
- 2.2.3 Tol-Pal Complex
- 2.3 Bacterial Stress Responses Affecting Vesiculation
- 2.3.1 Envelope Stress Response
- 2.3.2 Cell Wall-Directed Agents
- 2.3.3 SOS Response and Bacteriophages
- 2.4 Filamentous or Tubular Surface Structures
- 2.5 Modulation of Outer Membrane Components or Composition
- 2.5.1 Pseudomonas Quinolone Signal (PQS)
- 2.5.2 LPS Modifications
- 2.5.2.1 Lipid A Modifications
- 2.5.2.2 LPS Core Modifications
- 2.5.2.3 O-Antigen Modifications
- 2.5.3 Modulation of Phospholipid Composition
- 2.6 Conclusion
- References
- Chapter 3: Biogenesis and Function of Extracellular Vesicles in Gram-Positive Bacteria, Mycobacteria, and Fungi
- 3.1 Introduction
- 3.2 Evidence for MVs in Cell-Walled Organisms
- 3.3 Methods for the Study of MVs in Organisms with a Thick Cell Wall
- 3.3.1 Methods of Isolation
- 3.3.2 Cargo Identification
- 3.3.2.1 Identification of MV-Associated Proteins
- 3.3.2.2 Identification of MV-Associated Lipids
- 3.3.2.3 Identification of MV-Associated Nucleic Acids
- 3.3.3 Quantification, Labeling, and Visualization of MVs
- 3.4 Mechanisms of MV Biogenesis in Cell-Walled Microorganisms
- 3.4.1 Fungi
- 3.4.2 Gram-Positive Bacteria and Mycobacteria
- 3.5 MV Cargo
- 3.5.1 Fungi
- 3.5.2 Gram-Positive Bacteria
- 3.5.3 Mycobacteria
- 3.6 Cell-Walled Organisms-Derived MV Functions
- 3.6.1 Fungi
- 3.6.2 Gram-Positive Bacteria
- 3.6.3 Mycobacteria
- 3.7 MVs in Medicine
- 3.7.1 Clinical Implications of MVs
- 3.7.2 MVs as Vaccine
- 3.7.3 MVs in Biofilm Production
- 3.7.4 MVs in Diagnosis
- 3.8 Unsolved Problems and Concluding Remarks
- 3.8.1 Cell Wall Transport
- 3.8.2 Mechanism of Vesicle Production and Sorting Contents
- 3.8.3 Role of Vesicles in Pathogenesis and Vaccines
- 3.9 Concluding Remarks
- References
- Chapter 4: Extracellular Vesicles in the Environment
- 4.1 Introduction