Bone regulators and osteoporosis therapy /

Bone regulators and osteoporosis therapy /

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Bibliographic Details
Imprint:	Cham : Springer, [2020]
Description:	1 online resource.
Language:	English
Series:	Handbook of experimental pharmacology ; volume 262 Handbook of experimental pharmacology ; v. 262.
Subject:	Osteoporosis -- Treatment. Osteoporosis -- Pathophysiology. Bones -- Pathophysiology. Pharmacology. Cell physiology. Cytokines. Growth factors. Metabolism -- Disorders. Proteins. Endocrinology. Bones -- Pathophysiology. Cell physiology. Cytokines. Endocrinology. Growth factors. Metabolism -- Disorders. Osteoporosis -- Treatment. Pharmacology. Proteins.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/12609298

Hidden Bibliographic Details
Other authors / contributors:	Stern, Paula H. (Pharmacologist), editor.
ISBN:	9783030573782 3030573788 303057377X 9783030573775
Notes:	Online resource; title from PDF title page (SpringerLink, viewed February 5, 2021).
Summary:	This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.
Other form:	Print version: 303057377X 9783030573775
Standard no.:	10.1007/978-3-030-57378-2

Table of Contents:

The cells of bone their interactions
Parathyroid hormone and bone
Vitamin D and bone
Gonadal hormones and bone
Thyroid hormones, glucocorticoids, insulin, and bone
Growth factors and bone
Prostaglandins and bone
Cytokines and bone: osteoimmunology
Chemokines and bone
Calcium and bone
FGF-23 and bone and mineral metabolism
Nervous system mediators and bone
Genetics of bone disorders
Osteoporosis pathogenesis
Structural and metabolic assessment of bone status
Osteoporosis Therapeutics 2019
New targets and emergent therapies for osteoporosis
Drugs causing bone loss
Natural Products as potential bone therapies.