Organotypic models in drug development /
Saved in:
| Imprint: | Cham, Switzerland : Springer, [2021] |
|---|---|
| Description: | 1 online resource (viii, 323 pages) : illustrations (some color). |
| Language: | English |
| Series: | Handbook of experimental pharmacology, 0171-2004 ; volume 265 Handbook of experimental pharmacology ; v. 265. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/12611718 |
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| 245 | 0 | 0 | |a Organotypic models in drug development / |c Monika Schäfer-Korting, Silvya Stuchi Maria-Engler, Robert Landsiedel. |
| 264 | 1 | |a Cham, Switzerland : |b Springer, |c [2021] | |
| 300 | |a 1 online resource (viii, 323 pages) : |b illustrations (some color). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Handbook of experimental pharmacology, |x 0171-2004 ; |v volume 265 | |
| 520 | |a This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide. | ||
| 505 | 0 | |a Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- In Vitro Models of the Blood-Brain Barrier -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Engineered Heart Muscle Models in Phenotypic Drug Screens -- Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection -- Skin Disease Models In Vitro and Inflammatory Mechanisms: Predictability for Drug Development -- Immunocompetent Human Intestinal Models in Preclinical Drug Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing. | |
| 504 | |a Includes bibliographical references. | ||
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed April 15, 2021). | |
| 650 | 0 | |a Drug development. |0 http://id.loc.gov/authorities/subjects/sh97007921 | |
| 650 | 0 | |a Tissue engineering. |0 http://id.loc.gov/authorities/subjects/sh2003001133 | |
| 650 | 0 | |a Tissue culture. |0 http://id.loc.gov/authorities/subjects/sh85135588 | |
| 650 | 0 | |a Pharmacology, Experimental. |0 http://id.loc.gov/authorities/subjects/sh85100600 | |
| 650 | 7 | |a Drug development. |2 fast |0 (OCoLC)fst00898670 | |
| 650 | 7 | |a Pharmacology, Experimental. |2 fast |0 (OCoLC)fst01060280 | |
| 650 | 7 | |a Tissue culture. |2 fast |0 (OCoLC)fst01151481 | |
| 650 | 7 | |a Tissue engineering. |2 fast |0 (OCoLC)fst01151484 | |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Schäfer-Korting, Monika, |d 1952- |e editor. |0 http://id.loc.gov/authorities/names/n98001519 | |
| 700 | 1 | |a Stuchi Maria-Engler, Silvya, |e editor. | |
| 700 | 1 | |a Landsiedel, Robert, |e editor. |0 http://id.loc.gov/authorities/names/n2020181387 | |
| 776 | 0 | 8 | |i Print version: |z 9783030700621 |w (OCoLC)1233165147 |
| 830 | 0 | |a Handbook of experimental pharmacology ; |v v. 265. |x 0171-2004 |0 http://id.loc.gov/authorities/names/n42012274 | |
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| 928 | |t Library of Congress classification |a RM301.25 |l Online |c UC-FullText |u https://link.springer.com/10.1007/978-3-030-70063-8 |z Springer Nature |g ebooks |i 12627326 | ||