Evolution of the human genome. II, Human evolution viewed from genomes /

Evolution of the human genome. II, Human evolution viewed from genomes /

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Bibliographic Details
Imprint:Tokyo : Springer, 2021.
Description:1 online resource (264 p.).
Language:English
Series:Evolutionary Studies
Evolutionary studies.
Subject:
Human genome.
Human genetics.
Evolution (Biology)
Evolution (Biology)
Human genetics.
Human genome.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12613314
Hidden Bibliographic Details
Varying Form of Title:Human evolution viewed from genomes
Other authors / contributors:Saitou, Naruya, editor.
ISBN:9784431569046
4431569049
9784431569022
4431569022
9784431569039
4431569030
9784431569053
4431569057
Digital file characteristics:text file PDF
Notes:3.2 High-Altitude Human Populations.
Includes index.
Online resource; title from PDF title page (SpringerLink, viewed June 8, 2021).
Summary:This two-volume set provides a general overview of the evolution of the human genome; The first volume overviews the human genome with descriptions of important gene groups. This second volume provides up-to-date, concise yet ample knowledge on the genome evolution of modern humans. It comprises twelve chapters divided into two parts discussing on-neutral Evolution on Human Genes (Part I) and evolution of Modern Human Populations (Part II.) The most significant feature of this book is the continent-wise discussion of modern human dispersal using human genomic data in Part II. Recent results such as introgression of paleogenomes to modern humans, new methods such as computer simulation of global human dispersals, and new information on genes for humanness will be of particular interest to the readers. Since the euchromatin regions of the human genome was sequenced in 2003, a huge number of research papers were published on modern human evolution for a variety of populations. It is now time to summarize these achievements. This book stands out as the most comprehensive book on the modern human evolution, focusing on genomic points of view with a broad scope. Primary target audiences are researchers and graduate students in evolutionary biology.
Other form:Print version: Saitou, Naruya Evolution of the Human Genome II Tokyo : Springer Japan,c2021 9784431569022
Standard no.:10.1007/978-4-431-56904-6
Table of Contents:
  • Intro
  • Preface
  • Contents
  • Part I: Non-neutral Evolution on Human Genes
  • Chapter 1: Anthropogeny
  • 1.1 Getting at the Origins of the Human Phenomenon
  • 1.2 Our Evolutionary Roots
  • 1.2.1 Homo Sapiens: The Paradoxical Ape
  • 1.2.2 Measuring Genetic Distance
  • 1.2.3 Ancient Genome Data
  • 1.2.4 Limits to Detecting Ancient Selection
  • 1.2.5 Phenotypes Are More Than Nucleic Acids and Proteins
  • 1.3 Phenotypes: From Fossils to Past Behavior, Current Physiology, and Cognition
  • 1.3.1 Fossil Data
  • 1.3.2 Archeological Data: Fossilized Behavior
  • 1.3.3 Stable Isotopes, Paleoclimate, and Paleonutrition
  • 1.3.4 Learning from Living Foragers
  • 1.3.5 The Holocene Trap
  • 1.3.6 Biological Proxies for Past Behavior
  • 1.3.7 The Crying Need for Phenotypic Data of Non-human Hominids
  • 1.3.8 Niche Construction and Top-Down Effects
  • 1.3.9 The Physical Niche
  • 1.3.10 The Socio-Cognitive Niche
  • 1.4 The Cultural Niche
  • 1.5 Language and Theory of Mind
  • 1.5.1 The Brain Needs the Body and the Group
  • 1.6 Opportunities and Limitations
  • 1.7 Open Minds, Closed Umbrellas
  • 1.7.1 The Need for Transdisciplinarity
  • 1.8 Why Anthropogeny?
  • 1.9 Note of Caution
  • References
  • Chapter 2: Positive Selection in Human Populations: Practical Aspects and Current Knowledge
  • 2.1 Statistical Approaches to Identify Signals of Positive Selection
  • 2.1.1 Using Polymorphism Data
  • 2.1.1.1 Tests Based on Long Haplotypes
  • 2.1.1.2 Tests Based on Site Frequency Spectrum
  • 2.1.1.3 Tests Based on Genetic Differentiation
  • 2.2 Practical Challenges in Detecting Positive Selection Using Polymorphism Data
  • 2.2.1 Distortions Due to Ascertainment Bias
  • 2.2.2 The Confounding Factor of Background Selection
  • 2.2.3 Demography Can Mimic Positive Selection
  • 2.2.3.1 Migration and Structure
  • 2.2.3.2 Population Expansion
  • 2.2.3.3 Population Bottleneck
  • 2.2.3.4 Founder Effect
  • 2.2.4 Has a Region of Interest Evolved Under Positive Selection?
  • 2.2.4.1 Using Simulations Accounting for Demography
  • 2.2.4.2 Outlier Approach
  • 2.2.4.3 Combination of Different Tests
  • 2.2.5 Selection Not Only by Hard Sweep
  • 2.2.5.1 Soft Sweep
  • 2.2.5.2 Polygenic Adaptation
  • 2.2.5.3 Recent Methodological Advances in Detecting Alternative Sweep Scenarios
  • 2.2.6 From Putative Advantageous Mutation to Increased Fitness
  • 2.3 Current Knowledge on Positive Selection in the Human Genome
  • 2.3.1 Candidate Gene Studies of Positive Selection
  • 2.3.2 Genome-Wide Scans for Positive Selection
  • 2.3.3 Insights from Published Studies of Positive Selection in Humans
  • 2.3.3.1 Functional Categories for the Selected Protein-Coding Genes
  • 2.3.3.2 Complex Adaptive Traits
  • 2.3.3.3 The Importance of Regulatory Elements
  • 2.4 Concluding Remarks
  • References
  • Chapter 3: Population Genomics of High-Altitude Adaptation
  • 3.1 Background

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