Colon cancer diagnosis and therapy. Volume 2 /

Colon cancer diagnosis and therapy. Volume 2 /

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Bibliographic Details
Imprint:Cham : Springer, 2021.
Description:1 online resource (459 p.)
Language:English
Subject:
Colon (Anatomy) -- Cancer -- Diagnosis.
Colon (Anatomy) -- Cancer -- Treatment.
Rectum -- Cancer -- Treatment.
Rectum -- Cancer -- Diagnosis.
Colon (Anatomy) -- Cancer -- Diagnosis.
Colon (Anatomy) -- Cancer -- Treatment.
Rectum -- Cancer -- Diagnosis.
Rectum -- Cancer -- Treatment.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12614131
Hidden Bibliographic Details
Other authors / contributors:Vishvakarma, Naveen Kumar.
Nagaraju, Ganji Purnachandra.
Shukla, Dhananjay.
ISBN:9783030646684
3030646688
9783030646677
Notes:6.1.2 Microflora.
Includes index.
Online resource; title from PDF title page (SpringerLink, viewed June 21, 2021).
Summary:Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.
Other form:Print version: Vishvakarma, Naveen Kumar Colon Cancer Diagnosis and Therapy Cham : Springer International Publishing AG,c2021 9783030646677
Standard no.:10.1007/978-3-030-64668-4
Table of Contents:
  • Intro
  • Preface
  • Contents
  • About the Editors
  • Chapter 1: Application of Single Cell Technology in Colorectal Cancer
  • 1.1 Introduction
  • 1.2 Isolation Methods for Single Cells and Recent Developments in Single Cell Techniques
  • 1.2.1 Single Cell Genome (DNA) Sequencing
  • 1.2.2 Single Cell Transcriptome (RNA) Sequencing
  • 1.2.3 Single Cell Epigenome Sequencing: DNA Methylation and Histone Sequencing
  • 1.3 Applications
  • 1.4 Conclusion
  • References
  • Chapter 2: Dietary Habits and Global Incidence of Colon Cancer
  • 2.1 Introduction
  • 2.2 The Difference in Dietary Habits
  • 2.2.1 The Western Diet
  • 2.2.2 Mediterranean Diet (MeD)
  • 2.2.3 African Diet
  • 2.2.4 Asian Diet
  • 2.2.4.1 Chinese Diet
  • 2.2.4.2 Japanese Diet
  • 2.3 Fruits and Vegetables (F&V)
  • 2.3.1 Dietary Fiber
  • 2.4 Grains
  • 2.5 Meat
  • 2.6 Carcinogens Produced by Cooking Methods
  • 2.6.1 Barbecue (BBQ)/Grilling
  • 2.6.2 Frying
  • 2.6.3 Roasting
  • 2.7 Carcinogen from Food Processing
  • 2.8 Carcinogen from Food Preservation
  • 2.8.1 Salt
  • 2.8.2 Monosodium Glutamate (MSG)
  • 2.9 Carcinogen from Pesticide Uses
  • 2.10 Environment Pollutants
  • 2.10.1 Aflatoxins (AFB1)
  • 2.11 Carcinogen from Water
  • 2.12 Role of Lifestyle Factors
  • 2.12.1 Obesity
  • 2.12.2 Physical Inactivity
  • 2.12.3 Alcohol Consumption
  • 2.12.4 Smoking
  • 2.13 Immune Status
  • 2.14 Conclusion
  • References
  • Chapter 3: Diet and Colon Cancer: A Comprehensive Review
  • 3.1 Introduction
  • 3.2 Role of Nutrients in CRC
  • 3.3 Calcium
  • 3.4 Vitamin D
  • 3.5 Dietary Fiber
  • 3.6 Foods
  • 3.7 Meat
  • 3.8 Dairy Products
  • 3.9 Fruits and Vegetables
  • 3.10 Whole Grain
  • 3.11 Dietary Pattern
  • 3.12 Conclusion and Future Direction
  • References
  • Chapter 4: Recent Therapeutic Strategies for the Treatment of Colon Cancer
  • 4.1 Introduction
  • 4.2 Molecular Aspects of Colon Cancer
  • 4.3 Diagnostic and Therapeutic Targets of Colorectal Cancer
  • 4.3.1 Treatment Approaches to Colon Cancer
  • 4.3.1.1 Conventional Methods
  • Surgery/Polypectomy
  • Radiation Therapy
  • Chemotherapy
  • Targeted Therapy
  • 4.3.1.2 Advanced Approaches to Treat Colon Cancer
  • Immunotherapy
  • Cancer Vaccines
  • Cellular Therapies
  • Gene Therapies
  • Combination Therapies
  • Nutritional Supplement Therapies
  • References
  • Chapter 5: Role of Bacteria in the Development of Cancer
  • 5.1 Introduction
  • 5.2 Bacterial Factors Involved in Cancer Development
  • 5.2.1 Cell Surface Components
  • 5.2.2 Bacterial Toxins
  • 5.2.3 Bacterial Effector Proteins
  • 5.2.4 Other Factors
  • 5.3 Bacterial Species Involved in Colon Cancer Development
  • 5.3.1 Escherichia coli
  • 5.3.2 Salmonella enterica
  • 5.3.3 Fusobacterium nucleatum
  • 5.3.4 Bacteroides fragilis
  • 5.3.5 Streptococcus gallolyticus
  • 5.3.6 Enterococcus faecalis
  • 5.4 Conclusions
  • References
  • Chapter 6: Role of Bacterial Infection (H. pylori) in Colon Carcinogenesis and Therapeutic Approaches
  • 6.1 Introduction
  • 6.1.1 Colorectal Polyp

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