Gene editing : an update /
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| Imprint: | Oakville, ON : Delve Publishing, 2019. |
|---|---|
| Description: | 1 online resource (250 pages) |
| Language: | English |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/12648627 |
Table of Contents:
- Cover; Half Title Page; Title Page; Copyright Page; Declaration; About the Editors; Table of Contents; List of Contributors; List of Abbreviations; Preface; Chapter 1 Gene editing: What is about?; 1.1 Introduction; 1.2 Principle of Gene Editing; 1.3 Gene Editing: Approaches; 1.4 Delivery of Tools Used For Editing; 1.5 What Does The Future Look Like?; 1.6 A Summary of Tools Used In Gene Editing; 1.7 Crispr Cas: A Tool; 1.8 The Path of Gene Editing; 1.9 Summary; 1.10 References; Chapter 2 Tools For Genomic Editing; 2.1 Introduction; 2.2 Principle; 2.3 Tool 1: RNA Interference
- 2.4 Tool 2: Meganucleases2.5 Tool 3: ZFN; 2.6 Tool 4: Talens; 2.7 Tool 5: Targetron; 2.8 Tool 6: Pentatricopeptide Repeat Proteins; 2.9 Tool 7: Adenine Base Editor; 2.10 Tool 8: Cisgenesis; 2.11 Tool 9: Oligonucleotide-Directed Mutagenesis; 2.12 Tool 10: Sgn; 2.13 Tool 11: Recombinases; 2.14 Tool 12: Riboswitches; 2.15 Tool 13: Oligomers; 2.16 Summary; 2.17 References; Chapter 3 CRISPR Cas System of Gene Editing; 3.1 Introduction; 3.2 Principle of CRISPR-Cas9; 3.3 Cas 9 And Gene Editing: Rationale; 3.4 Advantages of CRISPR Cas; 3.5 Variants of Cas9; 3.6 Delivery of Cas9; 3.7 Recent Research
- 3.8 Boosting The Efficiency of CRISPR Cas3.9 Summary; 3.10 References; Chapter 4 Case Studies of The Use of Gene Editing; 4. 1 Introduction; 4.2 Genome Editing In Plants; 4.3 Case Study: Seed Oil Composition And Gene Editing; 4.4 Case Study: Human Serum Albumin In Rice; 4.5 Cas9 Systems And Use In Plants; 4.6 Plastid Genomes To Be Edited; 4.7 Genome Editing And HIV; 4.8 Ngago; 4.9 Gene Editing Of Livestock; 4.10 Summary; 4.11 References; Chapter 5 Role of Gene Editing: Applications, Issues And Ethics; 5.1 Potential Of Gene Editing; 5.2 Genome Editing And Human Subjects
- 5.3 Human Embryos And Editing5.4 CRISPR Cas9 Tool: Potential; 5.5 Issues With CRISPR Technology And Gene Editing; 5.6 Editing Somatic Cells; 5.7 Summary; 5.8 References; Chapter 6 Targeting Human MicroRNA Genes Using Engineered Tal-Effector Nucleases (TALENS); Abstract; Introduction; Results; Discussion; Materials And Methods; Acknowledgments; Author Contributions; References; Chapter 7 Genome Editing In Plants: An Overview Of Tools And Applications; Abstract; Introduction; Mechanisms of Genome Editing Systems; Practical Applications of Genome Editing Systems
- Safety Assessment Aspects of Genome Editing SystemsMultitude of Advantages And Perspectives of Geens; Conclusion; Acknowledgments; References; Chapter 8 Using CRISPR/Cas9 To Knock Out Amylase In Acinar Cells Decreases Pancreatitis-Induced Autophagy; Abstract; Introduction; Materials And Methods; Results; Conclusions; Acknowledgments; References; Chapter 9 Editing of The Human TRIM5 Gene To Introduce Mutations With The Potential To Inhibit HIV-1; Abstract; Introduction; Results; Discussion; Methods; Acknowledgments; References; Chapter 10 The Rise of CRISPR/Cas For Genome Editing In Stem Cells.