Hyperpolarized carbon-13 magnetic resonance imaging and spectroscopy /
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| Imprint: | [Place of publication not identified] : Academic Press, 2021. |
|---|---|
| Description: | 1 online resource |
| Language: | English |
| Series: | Advances in magnetic resonance technology and applications ; v. 3 Advances in magnetic resonance technology and applications ; v. 3. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/12874149 |
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| 245 | 0 | 0 | |a Hyperpolarized carbon-13 magnetic resonance imaging and spectroscopy / |c edited by Peder E.Z. Larson. |
| 264 | 1 | |a [Place of publication not identified] : |b Academic Press, |c 2021. | |
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| 490 | 1 | |a Advances in magnetic resonance technology and applications ; |v v. 3 | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover -- HYPERPOLARIZED CARBON-13 MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY -- HYPERPOLARIZED CARBON-13 MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY -- Copyright -- Series list -- Contents -- Contributors -- Preface -- Organization -- Prerequisites -- Acknowledgments -- 1 -- The physics of dissolution Dynamic Nuclear Polarization -- 1.1 Introduction -- 1.2 Polarization, magnetization, sensitivity, and hyperpolarization -- 1.3 Methods of hyperpolarization -- 1.4 Dynamic Nuclear Polarization -- 1.4.1 Solid effect -- 1.4.2 Cross-effect and thermal mixing | |
| 505 | 8 | |a 1.5 The DNP sample: formulation of the imaging agent and the electron paramagnetic agent -- 1.6 Dissolution and relaxation -- 1.7 Conclusion -- References -- 2 -- Hardware for preparing HP 13C-molecules: from polarizer to patient -- 2.1 Requirements for DNP -- 2.1.1 The magnet -- 2.1.2 Cryogenic environment -- 2.1.3 Microwaves -- 2.1.4 The sample -- 2.2 Monitoring of solid-state 13C polarization -- 2.3 Rapid state change -- 2.4 Preclinical dDNP -- 2.5 Postdissolution -- 2.6 Clinical dDNP -- 2.6.1 Quality control -- 2.7 Future developments -- 2.8 Conclusions -- Acknowledgments -- References | |
| 505 | 8 | |a 3 -- HP acquisition methods: pulse sequences, reconstruction, and RF coils -- 3.1 Introduction -- 3.2 Hyperpolarized imaging considerations -- 3.2.1 T1 decay and nonrecoverable magnetization -- 3.2.2 RF decay and metabolism -- 3.2.3 Chemical shift displacement -- 3.3 Pulse sequences and reconstruction -- 3.3.1 Nonselective spectroscopy and CSI -- 3.3.2 Fast spectroscopic imaging -- 3.3.3 IDEAL CSI -- 3.3.4 Metabolite-selective imaging -- 3.3.5 Pulse sequence summary -- 3.4 RF coils -- 3.4.1 Surface and volume coils -- 3.4.2 Multichannel arrays and coil combination -- 3.5 Summary -- References | |
| 505 | 8 | |a 4 -- HP experimental methods: cells and animals -- 4.1 Introduction -- 4.2 Dissolution-What is in it? -- 4.3 Transfer to the magnet-how fast can you run? -- 4.4 Delivery-how much and how to? -- 4.4.1 How much of the hyperpolarized agent is sufficient? -- 4.4.2 How to deliver the hyperpolarized agent? -- 4.5 Preclinical model systems for testing of hyperpolarized 13C agents -- 4.5.1 Models used for feasibility testing -- 4.5.2 Models used for HP agent development for a predetermined biomedical application -- 4.5.3 Preclinical animal models used in hyperpolarized NMR | |
| 505 | 8 | |a 4.6 Understanding and interpreting the hyperpolarized signals to shed light on the underlying biochemistry of the pathology -- Acknowledgments -- References -- Further study -- 5 -- HP agents and biochemical interactions -- 5.1 Introduction -- 5.1.1 Main differences between 1H MRI and HP 13C spectroscopy and imaging -- 5.1.2 Ideal characteristics of an HP 13C agent -- 5.1.3 Carbon-13 magnetic resonance and labeled metabolic substrates -- 5.2 Overview of biological HP agents -- 5.2.1 [1-13C]pyruvate -- 5.2.2 [1,4-13C2]Fumarate -- 5.2.3 Carbohydrates -- 5.2.4 Fatty acids and ketone bodies | |
| 650 | 0 | |a Magnetic resonance imaging. |0 http://id.loc.gov/authorities/subjects/sh85079741 | |
| 650 | 0 | |a Electron paramagnetic resonance. |0 http://id.loc.gov/authorities/subjects/sh85042228 | |
| 650 | 2 | |a Magnetic Resonance Imaging |0 https://id.nlm.nih.gov/mesh/D008279 | |
| 650 | 6 | |a Imagerie par résonance magnétique. | |
| 650 | 6 | |a Résonance paramagnétique électronique. | |
| 650 | 7 | |a electron spin resonance. |2 aat | |
| 650 | 7 | |a Electron paramagnetic resonance. |2 fast |0 (OCoLC)fst00906698 | |
| 650 | 7 | |a Magnetic resonance imaging. |2 fast |0 (OCoLC)fst01005780 | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Larson, Peder E. Z., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Hyperpolarized carbon-13 magnetic resonance imaging and spectroscopy. |d [Place of publication not identified] : Academic Press, 2021 |z 0128222697 |w (OCoLC)1220992820 |
| 830 | 0 | |a Advances in magnetic resonance technology and applications ; |v v. 3. | |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/bookseries/26669099/3 |y Elsevier |
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