Cancer immunoprevention : methods and protocols /

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Bibliographic Details
Imprint:	New York, NY : Humana Press, [2022] ©2022
Description:	1 online resource (xi, 227 pages) : illustrations (chiefly color).
Language:	English
Series:	Methods in molecular biology, 1940-6029 ; 2435 Methods in molecular biology (Clifton, N.J.) ; v. 2435.
Subject:	Cancer -- Prevention. Cancer -- Immunotherapy. Immunological adjuvants. Cancer -- Immunotherapy. Cancer -- Prevention. Immunological adjuvants.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/12942565

Hidden Bibliographic Details
Other authors / contributors:	McAllister, Florencia, editor.
ISBN:	9781071620144 1071620142 9781071620137
Notes:	Includes index. Online resource; title from PDF title page (SpringerLink, viewed January 11, 2022).
Summary:	This volume provides methods and techniques to further the study of cancer immunoprevention. Chapters describe tumor-associated antigens, cancer immune-preventive vaccines, generation of TILs, development of monoclonal antibodies, immunoprofiling technologies, tissue multispectral imaging techniques, mass cytometry on suspensions, mutiparametric flow cytometry, genomic expression analysis, and proteomic profiling of tumor microenvironment cell populations and metabolic assessment through novel imaging technologies. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Cancer Immunoprevention: Methods and Protocol aims to further understanding, development of interventional active strategies, and immune-interception of cancer.
Standard no.:	10.1007/978-1-0716-2014-4

Table of Contents:

Cancer Immunoprevention: General Concepts
Targets and Strategies for Cancer Immunoprevention
Discovery of targets for cancer immunoprevention
Antigen pulsed exosome vaccines for Immunoprevention
Isolation and Maintenance of Tumor-Infiltrating Lymphocytes for Translational & Clinical applications: established methods and new developments
Monoclonal Antibodies Generation: Updates and Protocols on Hybridoma Technology
Transcriptomic-Assisted Immune and Neoantigen Profiling in Premalignancy
Assessment of the Murine Tumor Microenvironment by Multiplex Immunofluorescence
Cytometry of Mass for Murine Immunoprofiling
Interrogating the tumor microenvironment by deep tissue immunoprofiling
Proteomic profiling of the tumor microenvironment
Metabolic Imaging using Hyperpolarization for Assessment of Premalignancy
Murine models for lineage tracing cancer initiating cells
Murine Model of Obesity-Induced Cancer.

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