How does germline regenerate? /

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Bibliographic Details
Author / Creator:MacCord, Kate, author.
Imprint:Chicago ; London : The University of Chicago Press, 2024.
Description:165 pages : illustrations ; 23 cm
Language:English
Series:Convening science: discovery at the Marine Biological Laboratory
Convening science.
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/13403348
Hidden Bibliographic Details
ISBN:9780226830490
0226830497
9780226830513
0226830519
9780226830506
Notes:Includes bibliographical references (pages 129-160) and index.
Summary:"Scientists have long held that we two have kinds of cells-germ and soma. Make a change to germ cells-say using genome editing-and that change will appear in the cells of future generations. Somatic cells are "safe" after such tampering; modify your skin cells, and your future children's skin cells will never know. And, while germ cells can give rise to new generations (including all of the somatic cells in a body), somatic cells can never become germ cells. How did scientists discover this relationship and distinction between somatic and germ cells-the so-called Weismann Barrier-and does it actually exist? Can somatic cells become germ cells in the way germ cells become somatic cells, that is, can germ cells regenerate from somatic cells even though conventional wisdom denies this possibility? Covering research from the late nineteenth century to the 2020s, historian and philosopher of science Kate MacCord explains how scientists came to understand and accept the dubious concept of the Weismann Barrier and the profound implications this convenient assumption has for research and policy, including on topics such as genome editing, stem cell research, and much more"--

MARC

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245 1 0 |a How does germline regenerate? /  |c Kate MacCord. 
264 1 |a Chicago ;  |a London :  |b The University of Chicago Press,  |c 2024. 
300 |a 165 pages :  |b illustrations ;  |c 23 cm 
336 |a text  |b txt  |2 rdacontent 
337 |a unmediated  |b n  |2 rdamedia 
338 |a volume  |b nc  |2 rdacarrier 
490 1 |a Convening science: discovery at the Marine Biological Laboratory 
504 |a Includes bibliographical references (pages 129-160) and index. 
505 0 |a Uncovering Assumptions That Have Shaped Germ Cell Science -- Backgrounding Conflicts within Germ Cell Science -- Challenging Assumptions in Germline Science -- Implications of Reenvisioning Germline Regeneration. 
520 |a "Scientists have long held that we two have kinds of cells-germ and soma. Make a change to germ cells-say using genome editing-and that change will appear in the cells of future generations. Somatic cells are "safe" after such tampering; modify your skin cells, and your future children's skin cells will never know. And, while germ cells can give rise to new generations (including all of the somatic cells in a body), somatic cells can never become germ cells. How did scientists discover this relationship and distinction between somatic and germ cells-the so-called Weismann Barrier-and does it actually exist? Can somatic cells become germ cells in the way germ cells become somatic cells, that is, can germ cells regenerate from somatic cells even though conventional wisdom denies this possibility? Covering research from the late nineteenth century to the 2020s, historian and philosopher of science Kate MacCord explains how scientists came to understand and accept the dubious concept of the Weismann Barrier and the profound implications this convenient assumption has for research and policy, including on topics such as genome editing, stem cell research, and much more"--  |c Provided by publisher. 
650 0 |a Germ cells. 
650 0 |a Somatic cells. 
650 0 |a Cells. 
650 6 |a Cellules germinales. 
650 6 |a Cellules somatiques. 
650 6 |a Cellules. 
830 0 |a Convening science. 
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927 |t Library of Congress classification  |a QL964.M33 2024  |l ASR  |c SPCLASR-UCPress  |b 115089727  |i 10696284