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|a R853.A53
|b S77 2022eb
|
| 049 |
|
|
|a MAIN
|
| 100 |
1 |
|
|a Striedter, Georg F.,
|d 1962-
|e author.
|0 http://id.loc.gov/authorities/names/n2004012807
|
| 245 |
1 |
0 |
|a Model systems in biology :
|b history, philosophy, and practical concerns /
|c Georg Striedter.
|
| 264 |
|
1 |
|a Cambridge, Massachusetts :
|b The MIT Press,
|c [2022]
|
| 300 |
|
|
|a 1 online resource (1 volume)
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
|
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|a computer
|b c
|2 rdamedia
|
| 338 |
|
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|a online resource
|b cr
|2 rdacarrier
|
| 504 |
|
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|a Includes bibliographical references and index.
|
| 520 |
|
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|a "Instead of arguing for a specific animal model, Striedter will review the history and philosophy of animal models in biomedical research, examining their various advantages and limitations"--
|c Provided by publisher.
|
| 588 |
0 |
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|a Print version record.
|
| 505 |
0 |
|
|a Intro -- Contents -- Preface -- 1. Crises in Biomedical Research -- 1.1 The Translatability Crisis -- 1.2 The Replicability Crisis -- 1.3 Reckoning with Biological Variation -- 1.4 Which Model Is "Best"? -- 1.5 This Book's Approach and Organization -- 2. Philosophy of Models in Biology -- 2.1 Abstract Models -- 2.2 Material Models -- 2.3 Assumptions about Model Fidelity -- 2.4 Dealing with Biological Complexity -- 2.5 Animal Welfare and Cognitive Dissonance -- 2.6 Comparative Biology and August Krogh Revisited -- 3. A History of Animal Models -- 3.1 Eclectic Beginnings of Biology
|
| 505 |
8 |
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|a 3.2 Early Experimental Medicine: Research on Pet Species -- 3.3 Fruit Flies: The First Supermodel -- 3.4 Laboratory Rats: The First Standardized Mammals -- 3.5 Laboratory Mice: From Cancer Fighter to Model Organism -- 3.6 Nonhuman Primates -- 3.7 The Rest of the Menagerie -- 3.8 Model System Ecology -- 4. A History of in Vitro Models -- 4.1 Microbial Models -- 4.2 Cell and Tissue Culture Models -- 4.3 Alternative Models in Toxicology -- 4.4 Model Ecology Revisited -- 5. Models and Therapies: Infectious Diseases, Cardiovascular Disease, and Cancer -- 5.1 Infectious Diseases
|
| 505 |
8 |
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|a 5.2 Cardiovascular Diseases -- 5.3 Cancers -- 5.4 Patterns of Model Use -- 6. Neurological Disorders: Trials and Tribulations -- 6.1 Brain and Spinal Cord Injuries -- 6.2 Neurodegenerative Disorders -- 6.3 Neuropsychiatric Disorders -- 6.4 Successes, Failures, Hopes -- 7. Diagnosis and Recommendations -- 7.1 Four Perspectives on Models in Biology -- 7.2 Recommendations -- 7.3 Conclusion -- Appendix -- References -- Index
|
| 650 |
|
0 |
|a Animal models in research.
|0 http://id.loc.gov/authorities/subjects/sh85005212
|
| 650 |
|
0 |
|a Animal experimentation.
|0 http://id.loc.gov/authorities/subjects/sh85005173
|
| 650 |
|
2 |
|a Animal Experimentation
|0 (DNLM)D032761
|
| 650 |
|
6 |
|a Modèles animaux dans la recherche.
|0 (CaQQLa)201-0127335
|
| 650 |
|
6 |
|a Expérimentation animale.
|0 (CaQQLa)201-0001372
|
| 650 |
|
7 |
|a Animal experimentation.
|2 fast
|0 (OCoLC)fst00809161
|
| 650 |
|
7 |
|a Animal models in research.
|2 fast
|0 (OCoLC)fst00809302
|
| 655 |
|
0 |
|a Electronic books.
|
| 655 |
|
4 |
|a Electronic books.
|
| 776 |
0 |
8 |
|i Print version:
|a Striedter, Georg F., 1962-
|t Model systems in biology.
|d Cambridge, Massachusetts : The MIT Press, [2022]
|z 9780262046947
|w (DLC) 2021033979
|w (OCoLC)1272882517
|
| 856 |
4 |
0 |
|u https://directory.doabooks.org/handle/20.500.12854/91422
|y Open Access Publishing in European Networks
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| 929 |
|
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|a oclccm
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| 999 |
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|t Library of Congress classification
|a R853.A53S77 2022eb
|l Online
|c UC-FullText
|u https://directory.doabooks.org/handle/20.500.12854/91422
|z Open Access Publishing in European Networks
|g ebooks
|i 13643688
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