The search for human chromosomes : a history of discovery /

The search for human chromosomes : a history of discovery /

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Bibliographic Details
Author / Creator:	Wall, W. J. (Wilson J.), author.
Imprint:	Cham : Springer, [2016] ©2016
Description:	1 online resource (vii, 179 pages) : illustrations (some color), portraits (some color)
Language:	English
Subject:	Human chromosomes. Chromosomes. Chromosomes Cytogenetics -- history Chromosomes, Human Chromosomes. Human chromosomes.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/13539750

Hidden Bibliographic Details
ISBN:	9783319263366 3319263366 9783319263342 331926334X
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references. Online resource; title from resource home page (ebrary, viewed April 4, 2016).
Summary:	"This book is a broadly historical account of a remarkable and very exciting scientific story-the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book"--Publisher's description
Other form:	Print version: Wall, Wilson John. Search for human chromosomes. Cham : Springer, [2016] 9783319263342
Standard no.:	10.1007/978-3-319-26336-6

Table of Contents:

Introduction
Background to the hunt for the human chromosome number
Microscopes and stains: the rise of technology
Mendel and genetics
Chromosomes as the carriers of heredity
Difficulties of chromosome handling and access to material
The implications of DNA structure
Tissue culture and the cell cycle: the answer is revealed
The flowering of clinical genetics
Sex and chromosomes
What we know, what we dont́ and where this may lead us.