The CRISPR/Cas system : emerging technology and application /

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Bibliographic Details
Imprint:Norfolk, UK : Caister Academic Press, 2017.
Description:1 online resource
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/13540437
Hidden Bibliographic Details
Other authors / contributors:Jamal, Muhammad, editor.
ISBN:9781910190647
1910190640
9781910190630
1910190632
9781910190630
Notes:Includes bibliographical references and index.
Vendor-supplied metadata.
Summary:The use of CRISPR/Cas technology for genome editing suggests many potential applications, including the alteration of the germline of humans, animals and food crops. The speed and efficiency of the CRISPR/Cas system make it a potentially useful system for gene therapy. In this volume expert international authors provide a useful and timely review of the applications of the CRISPR/Cas system across diverse fields and explore further avenues and research directions of this novel and powerful editing technology. The technology and its application are reviewed with respect to reproduction and development, immunity and genetic diseases, system structure and system specificity. Some of the potential problems of the CRISPR/Cas system are also discussed, in particular the specificity of the system: this remains an important topic as improvement could lead to the more direct and efficient use of the CRISPR/Cas system in clinical settings. The authors also debate ethical concerns associated with this powerful new technology. This volume is a rigorous review of the applications and new opportunities for the CRISPR/Cas system and provides a stimulus for current and future research. An invaluable guide for all scientists working in the fields of genome editing and gene therapy the book is also recommended for all life sciences libraries.

MARC

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245 0 4 |a The CRISPR/Cas system :  |b emerging technology and application /  |c edited by Muhammad Jamal, State Key Laboratory of Agricultural Microbiology College of Animal Science and Medicine, Huazhong Agricultural University, Wuhan, the People's Republic of China. 
264 1 |a Norfolk, UK :  |b Caister Academic Press,  |c 2017. 
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504 |a Includes bibliographical references and index. 
520 |a The use of CRISPR/Cas technology for genome editing suggests many potential applications, including the alteration of the germline of humans, animals and food crops. The speed and efficiency of the CRISPR/Cas system make it a potentially useful system for gene therapy. In this volume expert international authors provide a useful and timely review of the applications of the CRISPR/Cas system across diverse fields and explore further avenues and research directions of this novel and powerful editing technology. The technology and its application are reviewed with respect to reproduction and development, immunity and genetic diseases, system structure and system specificity. Some of the potential problems of the CRISPR/Cas system are also discussed, in particular the specificity of the system: this remains an important topic as improvement could lead to the more direct and efficient use of the CRISPR/Cas system in clinical settings. The authors also debate ethical concerns associated with this powerful new technology. This volume is a rigorous review of the applications and new opportunities for the CRISPR/Cas system and provides a stimulus for current and future research. An invaluable guide for all scientists working in the fields of genome editing and gene therapy the book is also recommended for all life sciences libraries. 
588 0 |a Vendor-supplied metadata. 
650 0 |a Genetic engineering.  |0 http://id.loc.gov/authorities/subjects/sh85053855 
650 0 |a Gene therapy.  |0 http://id.loc.gov/authorities/subjects/sh85053738 
650 0 |a Molecular genetics.  |0 http://id.loc.gov/authorities/subjects/sh85086586 
650 0 |a RNA editing.  |0 http://id.loc.gov/authorities/subjects/sh93000171 
650 0 |a Prokaryotes.  |0 http://id.loc.gov/authorities/subjects/sh85107388 
650 0 |a Genetics  |x Technique.  |0 http://id.loc.gov/authorities/subjects/sh85053881 
650 2 |a CRISPR-Cas Systems 
650 2 |a Genetic Techniques 
650 2 |a Genetic Therapy  |0 https://id.nlm.nih.gov/mesh/D015316 
650 6 |a Thérapie génique. 
650 6 |a Génétique moléculaire. 
650 6 |a ARN  |x Édition. 
650 6 |a Procaryotes. 
650 6 |a Systèmes CRISPR-Cas. 
650 6 |a Génétique  |x Technique. 
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650 7 |a Gene therapy.  |2 fast  |0 (OCoLC)fst00939638 
650 7 |a Genetic engineering.  |2 fast  |0 (OCoLC)fst00940027 
650 7 |a Molecular genetics.  |2 fast  |0 (OCoLC)fst01024797 
650 7 |a Prokaryotes.  |2 fast  |0 (OCoLC)fst01078852 
650 7 |a RNA editing.  |2 fast  |0 (OCoLC)fst01086255 
700 1 |a Jamal, Muhammad,  |e editor. 
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