Recombinant DNA vaccines : rationale and strategy /

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Bibliographic Details
Imprint:New York : Marcel Dekker, c1992.
Description:xiv, 409 p. : ill. ; 24 cm.
Language:English
Subject:
Format: E-Resource Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/1441447
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Other authors / contributors:Isaacson, Richard E., 1947-
ISBN:0824786998
Notes:Includes bibliographical references and index.
Table of Contents:
  • Introduction / Gary K. Schoolnik
  • Pt. 1. Rationale. 1. The Rationale for rDNA Vaccines / Richard E. Isaacson. 2. Modern Approaches to the Development of Attenuated Virus Strains / Anne Flamand. 3. Development of Nontoxic Immunogenic Analogs of Toxins for Vaccines with Emphasis on Pertussis Toxin / James L. Cowell, Robert A. Deich and Alan Kimura. 4. Bacterial Virulence as Strategies to Develop Vaccines / Steven Clegg. 5. Phase and Antigenic Variation of Bacterial Colonization Factors in the Development of Recombinant Vaccines / Barry I. Eisenstein, J. Michael Koomey and Per Klemm. 6. Antigenic Variation in Parasitic Protozoa / C. M. R. Turner. 7. Strategies to Achieve Mucosal Immunity / David F. Keren and Lawrence K. Silbart
  • Pt. 2. Strategy. 8. Cloning Strategies in Prokaryotes / John F. Barrett and Richard E. Isaacson. 9. The Utility of Fusion Proteins in the Development of Vaccines / Egon Amann. 10. Vaccinia Virus as a Cloning and Delivery System for Vaccines / Michael Mackett. 11. Baculovirus Expression Vectors / Donald L. Jarvis and Max D. Summers. 12. Use of Attenuated Bacteria as Live Oral Vaccine Vectors / John D. Clements, Jian Xiong Bao and Lucia Cardenas. 13. Minicells as Specialized Vaccines and Vaccine Carriers / George G. Khachatourians. 14. Rationale for the Design of Anti-Idiotypic Antibody Vaccines / Sybille Muller, Heinz Kohler and Darrell Anderson. 15. The Iscom--An Approach to Subunit Vaccines / Bror Morein and Lennart Akerblom. 16. Safety of Recombinant Vaccines / Edwin C. Hahn.