Mutant oncogenes : targets for therapy /

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Bibliographic Details
Edition:1st ed.
Imprint:London ; New York : Chapman & Hall Medical, 1993.
Description:x, 209 p. : ill. ; 26 cm.
Language:English
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/1448736
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Other authors / contributors:Lemoine, Nicholas R.
Epenetos, A. A.
ISBN:0412481103
Notes:Papers from an international conference held in London, in Sept. 1991.
Includes bibliographical references and index.
Table of Contents:
  • 1. Targeting the c-erbB-2 proto-oncogene with monoclonal antibodies / John W. Park, Paul Carter, Refaat Shalaby, Daniel Maneval and H. M. Shepard
  • 2. Oncogene products as targets for immunotherapy / S. Menard, R. Pellegrini, U. Srinivas, E. Tosi, M. Pompen, M. Caldera, M. Campiglio, G. Manenti and M. I. Colnaghi
  • 3. Humoral immune response against the c-erbB-2 oncoprotein in patients with breast carcinoma / S. Menard, S. M. Pupa, E. Colzani, S. Andreola, S. Martignone, R. Bufalino, F. Rilke, N. Cascinelli and M. I. Colnaghi
  • 4. Growth factor receptors as targets for antibody therapy / C. Dean, J. Styles, M. Valeri, H. Modjtahedi, A. Bakir, J. M. Babich and S. Eccles
  • 5. Antitumour activity of rat mAbs to the human receptor for EGF / H. Modjtahedi, J. Styles, G. Box, S. Eccles, B. Gusterson and C. Dean
  • 6. Growth factors in gastric carcinoma / M. I. Filipe, S. Jain, N. R. Lemoine and W. J. Gullick
  • 7. Differential expression of MR6 antigen and c-erbB-2 protein in breast tumours / Ishak B. Mat, Nancy Moors, David Melcher, Brian M. J. Foxwell and Mary A. Ritter
  • 8. The growing family of fibroblast growth factors and their receptors / Hing Y. Leung
  • 9. Immune surveillance and immunogenicity of nuclear and intracellular antigens / Mary A. Ritter
  • 10. Overview of ras oncogenes and their clinical potential / Nicholas R. Lemoine
  • 11. Transforming proteins as possible targets for immunotherapy of cancer / Hans J. Stauss and Li Yin
  • 12. Mutant ras oncogenes: targets for immunotherapy? / Tobias Gedde-Dahl III, Jon Amund Eriksen, Eick Thorsby and Gustav Gaudernack
  • 13. The effect of ras and transforming growth factors on major histocompatibility antigen expression / R. L. Darley and A. G. Morris
  • 14. Anti-sense oligonucleotides and ribozymes against ras / Ian Gibson
  • 15. Prospects for anti-ras chemotherapy / Karen A. Cadwallader and John F. Hancock
  • 16. Downregulation of protein kinase C in thyroid epithelium is selectively toxic for cells expressing mutant ras / Jane A. Bond, Tim Dawson, Nicholas R. Lemoine and David Wynford-Thomas
  • 17. Post-therapy fms and ras mutations and the effect of retinoids on cellular transformation / R. A. Padua, S. A. Ridge, G. Carter, P. G. Cachia, J. Thomas, E. Thompson, J. Whittaker and A. Jacobs
  • 18. The v-myc and v-jun oncogenes and their cellular cognates / David A. F. Gillespie
  • 19. Cancer genes on chromosome 17 - an overview / Alistair M. Thompson
  • 20. Tumour-suppressor genes RB1 and p53 in human breast cancer / Jenny M. Varley and Rosemary A. Walker
  • 21. p53 expression in human tumours: breast, lung, colon, bladder and prostate cancer; melanoma and lymphoma / Adrian L. Harris, Kevin Gatter, Elizabeth Horak, Lucas Kaklamanis, Francesco Pezzella, David P. Lane, David Neal and John Stretch
  • 22. The tumour-suppressor gene p53 in human pancreatic cancer / Claire M. Barton and Nicholas R. Lemoine
  • 23. p53 overexpression in gastric carcinoma is a prognostic indicator / M. I. Filipe, H. M. Martin and D. P. Lane
  • 24. Analysis of p53 mutations in human thyroid carcinoma / R. Donghi, A. Longoni, P. Michieli, G. Della Porta and M. A. Pierotti
  • 25. A phenotypically and karyotypically stable human thyroid epithelial line conditionally immortalized by SV40 T / Fiona S. Wyllie, Jane A. Bond, Tim Dawson, Denise White, Rose Davies and David Wynford-Thomas.