Vascular innervation and receptor mechanisms : new perspectives /
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Imprint: | San Diego : Academic Press, c1993. |
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Description: | xxi, 475 p. : ill. ; 23 cm. |
Language: | English |
Subject: | |
Format: | Print Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/1487856 |
Table of Contents:
- Ch. 1. Introduction: Changing Face of Autonomic and Sensory Nerves in the Circulation / G. Burnstock. II. The Vascular Neuromuscular Junction. III. Multiplicity of Transmitters; Cotransmission. IV. Sympathetic Perivascular Nerves. V. Parasympathetic Perivascular Nerves. VI. Sensory-Motor Perivascular Nerves. VII. Perivascular Nerves Arising from Intramural Neurons. VIII. Neural-Endothelial Interactions in Local Control of Vascular Tone. IX. Plasticity of Perivascular Nerves and Endothelial Cells
- Pt. I. Basic Studies. Ch. 2. Regulation of the Autonomic Innervation of Blood Vessels during Development and Aging / T. Cowen. II. The Establishment of Locally Specific Patterns of Innervation during Early Development. III. Regulation of Autonomic Neuronal Phenotype during Early Development. IV. Changes in the Nerve Supply to Blood Vessels during Maturity. V. Changes during Aging in Perivascular Nerves. VI. Regulatory Factors in Aging of Perivascular Nerves. Ch. 3. Endothelial-Derived Relaxing Factors: Focus on Nitric Oxide / S. M. Gardiner and T. Bennett. II. General Considerations. III. Biosynthesis of Nitric Oxide. IV. Whole Animal Studies with L-Arginine Analogs. V. Influence of Nitric Oxide in Different Regions of the Cardiovascular System. Ch. 4. The Effect of Endothelin on Circulation System / Tomoh Masaki. II. Cellular Mechanism of Endothelin-Induced Vasoconstriction. III. Hemodynamic Effect of Endothelin. IV. Regional System of Regulation of Vasoconstriction by Endothelin. V. Conversion from Big Endothelin to Endothelin. VI. Interaction of Endothelin to Other Factors. VII. Effect of Endothelin on Cardiac Muscle. VIII. Physiological and Pathophysiological Significance of Endothelin. Ch. 5. Interaction between Endothelium-Derived Vasoactive Factors and Neurohumoral Substances in the Regulation of Vascular Tone / Gabor M. Rubanyi. II. Endothelium-Derived Vasoactive Factors. III. Neurohumoral Substances and the Endothelium. IV. Physiological Significance. V. Pathological Consequences of Endothelial Dysfunction. Ch. 6. Modulation of Endothelial-Inflammatory Cell Interactions by Primary Afferent Nerves / Zeinab Khalil, Anthony Eglezos and Robert D. Helme. II. Neural Receptor Mechanisms. III. Interaction between Endothelial Cells and Leukocytes in Disease States
- Pt. II. The Sympathetic System. Ch. 7. Noradrenaline and Neuropeptide Y in the Sympathetic System: Prejunctional Interactions and Regulation of Release / Pia Linton-Dahlof and Carl Dahlof. II. Modulatory Mechanisms of Noradrenaline Release. III. Modulatory Mechanisms of NPY Release. Ch. 8. Neuropeptide Y Receptor Subtypes and Putative Receptor Ligands / Thomas Hedner, Xiang-Ying Sun and Lars Edvinsson. II. NPY Localization, Release, and Mechanisms in the Cardiovascular System. III. Structures of NPY, Peptide YY, and Pancreatic Polypeptide. IV. NPY Receptor Subtypes. V. NPY Signal Transduction. VI. NPY Receptor Ligands. Ch. 9. ATP as a Cotransmitter with Noradrenaline in Sympathetic Perivascular Nerves / Charles Kennedy. II. Vascular Actions of Purines. III. ATP as an Excitatory Cotransmitter in Sympathetic Nerves. IV. Role of ATP in Hypertension. V. Functional Significance of Cotransmission
- Pt. III. Parasympathetic Innervation of Circulation. Ch. 10. Regulatory Peptides of the Parasympathetic Vascular Innervation / Rolf Uddman, Rolf Hakanson, Anders Luts and Frank Sundler. II. Vasoactive Intestinal Peptide/Peptide Histidine Isoleucine. III. Neuropeptide Y. Ch. 11. Pharmacology of Acetylcholine and Vasoactive Intestinal Peptide in Perivascular Nerves / O. Rorstad, H. Shirahase and M. Huang. II. The Vascular Cholinergic System. III. The Vascular VIP System
- Pt. IV. Sensory Afferent System. Ch. 12. Pattern of Innervation of Sensory Afferent Systems in the Circulation: Immunocytochemistry and Ultrastructure / Sergio Gulbenkian and John Wharton. II. General Model of Innervation of Blood Vessels. III. Ultrastructure of Vascular Sensory Nerve Terminals. IV. Neuropeptides in Sensory Afferent Systems. Ch. 13. Calcitonin Gene-Related Peptide and Blood Vessels / Inger Jansen, Leif Nilsson and Lars Edvinsson. II. Responses to CGRP in Different Vascular Beds. III. Vasomotor Responses in Vitro. IV. Second-Messenger Studies. V. Ligand Binding Studies. VI. In Vivo Experiments. Ch. 14. Characterization of Neurokinin Receptors in the Circulation / Domenico Regoli, Nourredine Rouissi and Pedro D'Orleans-Juste. II. Neurokinins in Peripheral Vessels: Localization and Functions. III. Pharmacological Characterization of Neurokinin Receptors in Isolated Vessels. IV. Mediators and Second Messengers Involved in the Cardiovascular Effects of Neurokinins. V. Biochemical Characterization of Neurokinin Receptors: Binding Assays and Autoradiography. Ch. 15. Peptidergic Sensory Neurons in the Local Regulations of Splanchnic Blood Flow / Peter Holzer. II. Identity of Sensory Neurons Regulating Blood Flow. III. Splanchnic Circulation. IV. Perspectives for Physiology and Pathophysiology
- Pt. V. Clinical Application. Ch. 16. Neuropeptides in Human Cardiovascular Regulation / John Pernow. II. Sympathetic Nerves. III. Parasympathetic Nerves. IV. Sensory Nerves. Ch. 17. Perivascular Peptides (NPY, CGRP, and SP) in Hypertension and Congestive Heart Failure / Lars Edvinsson, David Erlinge, Thomas Hedner, Pavo Hedner, Thomas Thulin and Stig Valdemarsson. II. Hypertension. III. Congestive Heart Failure. Ch. 18. Perivascular Peptides in the Coronary Circulation: Relation to Pathophysiology / John Clarke. II. Neuropeptide Y. III. Calcitonin Gene-Related Peptide. IV. Tachykinins. V. Vasoactive Intestinal Polypeptide. VI. Endothelin. VII. Vasopressin. VIII. Somatostatin. IX. Renin - Angiotensin System. X. Cholecystokinin. XI. Neurotensin. XII. Atrial Natriuretic Peptide. XIII. Bradykinin. XIV. Transplant Denervation. XV. Growth Factor Activity. Ch. 19. Perivascular Peptides in Subarachnoid Hemorrhage / Roar Juul and Lars Edvinsson. II. Peptidergic Innervation of the Monkey Middle Cerebral Artery. III. Perivascular Nerves in Subarachnoid Hemorrhage (SAH). IV. Studies in Human SAH. V. Neuropeptide Y-LI. VI. Calcitonin Gene-Related Peptide-LI. VII. CSF Peptides in SAH. VIII. Infusion Studies. Ch. 20. Vasoactive Peptides in Migraine and Cluster Headache / Peter J. Goadsby. II. Neuroanatomy and Neurochemistry. III. Animal Studies. IV. Human Data. Ch. 21. Perivascular Peptides in the Respiratory Tract / J. G. Widdicombe. II. Vascular Anatomy. III. Parasympathetic Neuropeptides. IV. Sympathetic Neuropeptides. V. Sensory Neuropeptides. VI. Pathophysiological Considerations. Ch. 22. Gastrointestinal Circulation in Man and Animals: Regulation by Perivascular Peptides and Classical Neurotransmitters / Ove Lundgren. I. The Sympathetic Control of the Gastrointestinal Circulation. II. The Parasympathetic Control of the Gastrointestinal Vascular Beds. III. Intramural Nervous Control of the Gastrointestinal Vascular Beds.