Table of Contents:
- 1. The Need for New Vaccines. 1.1. Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy / Paul W. Ewald. 1.2. Economic Perspectives on Vaccine Needs / Robert V. Ashley and Christopher J. L. Murray. 1.3. Future Immunization Strategies - Considerations from the Public Health View / Sieghart Dittmann. 1.4. The Pertussis Vaccines / David L. Klein and Carole Heilman
- 2. General Principles of Immunology. 2.1. Basic Principles of Immunity Against Intracellular Bacteria and Protozoa / Gudrun Szalay and Stefan H. E. Kaufmann. 2.2. Viral Immunity and Vaccine Strategies / David L. Woodland, Geoffrey A. Cole and Peter C. Doherty. 2.3. Broadly Reactive HLA Restricted T Cell Epitopes and Their Implications for Vaccine Design / John Sidney, Ralph T. Kubo, Peggy A. Wentworth, Jeff Alexander, Robert W. Chestnut, Howard M. Grey and Alessandro Sette. 2.4. Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack / Peter Bretscher. 2.5. The Impact of the Type 1 and Type 2 T Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites / Christian Bogdan and Martin Rollinghoff
- 3. General Principles of Vaccinology. 3.1. Modern Adjuvants. Functional Aspects / Bror Morein, Karin Lovgren-Bentsson and John Cox. 3.2. Biodegradable Microspheres as Vehicles for Antigens / Gideon F. A. Kersten and Bruno Gander. 3.3. Peptide Based Vaccines / Hansjorg Schild and Hans-Georg Rammensee. 3.4. Recombinant Bacteria as Vaccine Carriers on Heterologous Antigens / Carlos E. Hormaeche and C. M. Anjam Khan. 3.5. Genetic Detoxification of Bacterial Toxins / Rino Rappuoli and Mariagrazia Pizza. 3.6. Recombinant Virus as Vaccination Carrier of Heterologous Antigens / Marion E. Perkus and Enzo Paoletti. 3.7. Naked DNA Vaccination / John W. Shiver, Jeffrey B. Ulmer, John J. Donnelly and Margaret A. Liu. 3.8. Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin / Jan Holmgren, Cecil Czerkinsky, Jia-Bin Sun and Ann-Mari Svennerholm
- 4. Specific Vaccination Strategies. 4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design / Paolo Ghiara, Antonello Covacci, John L. Telford and Rino Rappuoli. 4.2. Malaria Vaccination / Manuel E. Patarroyo and Roberto Amador. 4.3. Vaccination Against Schistosomiasis: Concepts and Strategies / Gilles J. Riveau and Andre Capron. 4.4. AIDS Vaccination / Stephen Norley and Reinhard Kurth. 4.5. Vaccination Therapy Against Autoimmune Diseases / Irun R. Cohen and Felix Mor.
