Growth factors as drugs for neurological and sensory disorders /
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| Imprint: | Chichester ; New York : J. Wiley & Sons, 1996. |
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| Description: | ix, 253 p. : ill. ; 24 cm. |
| Language: | English |
| Series: | Ciba Foundation symposium ; 196 Ciba Foundation symposium new ser., 196. |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/2512664 |
Table of Contents:
- Several neurotrophic factors have been shown to promote the growth, survival and differentiation of neurons
- This book brings together laboratory investigators and scientists involved in clinical trials to discuss the potential therapeutic use of these growth factors
- Included are details of several trials currently underway involving growth factors as treatments for neurological disorders such as amyotrophic lateral sclerosis, Alzheimers Disease, post-polio syndrome and diabetic and drug-induced neuropathies
- The relatively rapid pace at which neurotrophic factors are being brought into the clinical arena raises important questions involving scientific, practical and ethical issues: these are discussed
- The book also looks at the latest animal studies examining the potential use of growth factors for promoting regrowth of nerves innervating sensory receptors in the eye, nose and ear
- Finally, the technical problems of using growth factors as drugs are discussed
- Various approaches to the problem of neurotrophin delivery are considered in detail, including new approaches based on the implantation of genetically engineered cells
