The mobile receptor hypothesis : the role of membrane receptor lateral movement in signal transduction /
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| Author / Creator: | Jans, David A., 1950- |
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| Imprint: | Austin : R.G. Landes ; New York : Distributor, Chapman & Hall, ©1997. |
| Description: | 224 pages : illustrations ; 24 cm. |
| Language: | English |
| Series: | Molecular biology intelligence unit Molecular biology intelligence unit (Unnumbered) |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/2887059 |
| Summary: | Elucidates some critical mechanisms of biological cell phones, signal transmission at the level of the membrane, the primary transducer of extracellular signals represented by hormones, growth factor, and other chemicals. Elaborates the theory and experimental evidence that receptors can diffuse freely within the plane of the membrane and that the diffusion is what allows interactions between protein signaling components. The theory has been accepted for two decades, but little studied. The goal is to encourage researchers to think of the membrane as two-dimensional rather than one, as a lattice of sites for interactions rather than an inert barrier to keep insides of the cell in and everything else out. Annotation c. by Book News, Inc., Portland, Or. |
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| Physical Description: | 224 pages : illustrations ; 24 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 0412132818 9780412132810 1570594376 9781570594373 |
