The immunoglobulins : structure and function /

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Bibliographic Details
Author / Creator:Nezlin, R. S. (Roalʹd Solomonovich)
Imprint:San Diego : Academic Press, 1998.
Description:xiii, 269 p. : ill. (some col.) ; 24 cm.
Language:English
Subject:
Format: E-Resource Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/3173945
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ISBN:0125179707 (hc : alk. paper)
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface
  • Structural Aspects: General Characteristics of Immunoglobulin Molecules: Immunoglobulin Classes
  • Heterogeneity of Immunoglobulins
  • Detection and Isolation of Immunoglobulins
  • Proteolytic and Chemical Fragments of Immunoglobulins
  • Immunoglobulin Peptide Chains
  • Additional Peptide Chains
  • Immunoglobulin Fold (Domain)
  • Fab Portion
  • Fc Portion
  • Immunoglobulin Molecules
  • Carbohydrate Components of Immunoglobulins
  • Animal and Human Immunoglobulins: Low Vertebrates
  • Birds
  • Mammals
  • Human Immunoglobulins
  • Origin of Antibody Diversity in Mice and Humans
  • Evolutionary Aspects
  • Engineering Antibody Molecules: Problems of Serum Immunotherapy
  • Chimeric Antibody Molecules and Humanization
  • Minimal Antibody Fragment (Fv)
  • Production of Human Monoclonal Antibodies by Page-Display and Transgene Technologies
  • Engineering of Immunoglobulins with Novel Properties
  • Polymerization of IgG Molecules and Their Fragments
  • Bispecific Antibodies
  • Functional Aspects: Antigen-Combining Site: General Characteristics
  • Conformational Changes Linked with Antigen Binding
  • Complex of VH of Camelid Heavy Chain Antibodies with Antigen
  • Interaction of an Autoantibody (Rheumatoid Factor) with Fcg
  • Structural Aspects of Antibody Specificity
  • Modeling Antibody-Combining Sites
  • Structural Aspects of Catalytic Antibody Activity
  • Antigen-Recognizing Molecules Other Than Antibodies: T-Cell Antigen Receptor
  • Proteins of Major Histocompatibility Complex
  • Complexes of T-Cell Receptor and Peptide-MHC
  • CD1 Molecules
  • Natural Killer Cell Inhibitory Receptors
  • Comparison of Antigen Binding by Various Antigen-Recognizing Molecules
  • Interactions Outside the Antigen-Combining Site: Fc Receptor-Binding Sites
  • Complement-Binding Sites
  • Proteins Reacting with the Fc Portion
  • Proteins Reacting with the Fab Portion
  • Lectins
  • Molecular Chaperones
  • Bacterial Immunoglobulin-Binding Proteins
  • Segmental Movements of Immunoglobulin Molecules: General Aspects
  • Functional Aspects of Segmental Flexibility
  • Subject Index