Triple helix forming oligonucleotides /
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| Imprint: | Boston : Kluwer Academic Publishers, c1999. |
|---|---|
| Description: | xv, 297 p. : ill. ; 25 cm. |
| Language: | English |
| Series: | Perspectives in antisense science |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/3857994 |
Table of Contents:
- Foreword
- Section I. Background and Structural Aspects
- 1. The Antigene Strategy: Progress and Perspectives in Selective Gene Silencing
- 2. Triple-Helix Structure
- The Triple-Helix-Forming Oligonucleotide
- 3. Thermodynamic State Diagrams of Oligonucleotide Triple Helices
- 4. Imaging of Triplexes by Electron and Scanning Force Microscopy
- 5. Chemical Modifications of Triple Helix Forming Oligonucleotides
- 6. Triple Helix Formation with Modified Oligonucleotides
- 7. Oligonucleotides as Artificial DNases
- Section II. The Biology of Triple Helices
- 8. Potential Mechanisms of Action
- 9. Oligonucleotide Uptake and Delivery in Tissue Culture Cells
- 10. Triple-Stranded Complexes as Antigene Molecules: Transcription Inhibition Ex Vivo
- 11. Gene-Targeting Triple Helix Forming Purine Oligonucleotides
- 12. DNA Triple Helix as a Tool to Regulate Cytokine Gene Expression
- 13. Genome Modification by Triplex-Forming Oligonucleotides
- 14. Psoralen-Coupled Oligonucleotides: In Vivo Binding and Repair
- 15. Structure and Biology of H DNA
- 16. Triplex-Binding Proteins
- 17. RNA and Triple Helices
- Section III. New Developments and Applications
- 18. Triplexes Involving PNA
- 19. Triple Helix Stabilizing Agents
- 20. New Targets for Triple Helix Forming Oligonucleotides
- 21. Triplexes and Biotechnology
- Index
