| Summary: | This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases.<br> Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma.<br> Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma<br> discusses the efficacy of new medications<br> examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies<br> presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses<br> addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults<br> assesses differences and similarities between intrinsic and antigen-induced asthma<br> describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells<br> explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways<br> reviews the genetic basis of allergy, as well as risk factors for asthma<br> explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies<br> evaluates various agents with modulatory effects on normal and pathogenic immune responses<br> focuses on strategies for the prevention of childhood asthma and more!<br> Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.
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