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20240826200355.5 |
| 008 |
991007s1999 enka b 001 0 eng d |
| 010 |
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|a gb 99070046
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| 015 |
|
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|a GB99-70046
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| 020 |
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|a 0121878708
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| 035 |
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|a NJRGA1462020-B
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| 035 |
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|a (NjR)a1462020
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| 035 |
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|a 90058114
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| 040 |
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|a Uk
|c Uk
|d DLC
|d NjR
|d OrLoB-B
|d OCoLC
|
| 050 |
|
4 |
|a QH431
|b .C66 1999
|
| 082 |
0 |
4 |
|a 599.93
|2 21
|
| 100 |
1 |
|
|a Cooper, David N.
|q (David Neil),
|d 1957-
|1 http://viaf.org/viaf/113378217
|
| 245 |
1 |
0 |
|a Human gene evolution /
|c David N. Cooper.
|
| 260 |
|
|
|a Oxford :
|b Bios Scientific Publishers ;
|a San Diego, CA :
|b distributed exclusively throughout the United States by Academic Press,
|c 1999.
|
| 300 |
|
|
|a xvii, 490 p. :
|b ill. ;
|c 24 cm.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|0 http://id.loc.gov/vocabulary/contentTypes/txt
|
| 337 |
|
|
|a unmediated
|b n
|2 rdamedia
|0 http://id.loc.gov/vocabulary/mediaTypes/n
|
| 338 |
|
|
|a volume
|b nc
|2 rdacarrier
|0 http://id.loc.gov/vocabulary/carriers/nc
|
| 440 |
|
4 |
|a Human molecular genetics series
|
| 504 |
|
|
|a Includes bibliographical references and indexes.
|
| 505 |
0 |
0 |
|g Pt. 1.
|t Introduction and Overview.
|g 1.
|t Structure and function in the human genome.
|t Chromosome structure and function.
|t Gene organization and transcriptional regulation.
|t DNA methylation.
|t Repetitive sequence elements.
|t Genes, mutations and disease.
|g 2.
|t Evolution of the human genome.
|t Ancient genome duplications at the dawn of vertebrate evolution.
|t Mammalian genome evolution.
|t Primate evolution.
|t Sequencing the genomes of model organisms and humans --
|g Pt. 2.
|t Evolution of Gene Structure.
|g 3.
|t Introns, exons, and evolution.
|t Intron structure, function and evolution.
|t The evolution of alternative processing.
|t Exon structure and evolution.
|t Introns early or introns late?
|t Mechanisms of intron insertion and deletion.
|t Exon shuffling.
|t Pseudoexons.
|g 4.
|t Genes and gene families.
|t The origins of human genes.
|t Multigene families.
|t Convergent evolution.
|t Coevolution.
|g 5.
|t Promoters and transcription factors.
|t Promoters and enhancers.
|t Transcription factors.
|g 6.
|t Pseudogenes and their formation.
|t Pseudogene formation.
|t Gene loss/inactivation in primates --
|g Pt. 3.
|t Mutational Mechanisms in Evolution.
|g 7.
|t Single base-pair substitutions.
|t Single base-pair substitutions in evolution.
|t Mutations in pathology and evolution; two sides of the same coin.
|t The importance of evolutionary conservation in the study of pathological mutations at the protein level using human factor IX as a model.
|t Equilibrium of synonymous codon substitutions.
|t Single base-pair substitutions in gene regions.
|g 8.
|t Contractions and expansions in gene size and number.
|t Gross gene deletions in evolution.
|t Microdeletions in evolution.
|t Microinsertions in evolution.
|t Insertion of transposable elements in evolution.
|t Gross gene duplications in evolution.
|t Intragenic gene duplications in evolution.
|t Coding sequence expansion and contraction resulting from the introduction or removal of initiation and termination codons.
|t Minisatellites, microsatellites and telomeric repeats.
|t Expansion of unstable repeat sequences.
|g 9.
|t Gross gene rearrangements.
|t Inversions.
|t Translocations and transpositions.
|t Gene fusion.
|t Recombination.
|t Gene conversion.
|t Gene creation by retrotransposition.
|g 10.
|t Molecular reconstruction of ancient genes/proteins.
|t Molecular reconstruction and homology modelling of the catalytic domain of the common ancestor of the hemostatic vitamin K-dependent serine proteases.
|t Indices of Human Gene Symbols used in the text.
|
| 650 |
|
0 |
|a Human genetics.
|0 http://id.loc.gov/authorities/subjects/sh85062875
|
| 650 |
|
0 |
|a Molecular genetics.
|0 http://id.loc.gov/authorities/subjects/sh00006394
|
| 650 |
|
0 |
|a Mutation (Biology)
|0 http://id.loc.gov/authorities/subjects/sh85089128
|
| 650 |
|
7 |
|a Genetics.
|2 fast
|0 http://id.worldcat.org/fast/fst00940117
|
| 650 |
|
7 |
|a Genomes.
|2 fast
|0 http://id.worldcat.org/fast/fst00940225
|
| 650 |
|
7 |
|a Molecular evolution.
|2 fast
|0 http://id.worldcat.org/fast/fst01024792
|
| 650 |
|
7 |
|a Mutagenesis.
|2 fast
|0 http://id.worldcat.org/fast/fst01031137
|
| 650 |
|
7 |
|a Transcription factors.
|2 fast
|0 http://id.worldcat.org/fast/fst01154564
|
| 901 |
|
|
|a ToCBNA
|
| 903 |
|
|
|a HeVa
|
| 035 |
|
|
|a (OCoLC)44721157
|
| 929 |
|
|
|a cat
|
| 999 |
f |
f |
|i 8ffcd82f-764c-523a-84c3-b86b53b84f4a
|s 46b4027c-a2d4-55fa-baef-5101f759d15a
|
| 928 |
|
|
|t Library of Congress classification
|a QH431 .C66 1999
|l JCL
|c JCL-Sci
|i 4377511
|
| 927 |
|
|
|t Library of Congress classification
|a QH431 .C66 1999
|l JCL
|c JCL-Sci
|e CRERAR
|b 55941421
|i 6812345
|
