DNA alterations in cancer : genetic and epigenetic changes /

DNA alterations in cancer : genetic and epigenetic changes /

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Bibliographic Details
Imprint:	Natick, MA : Eaton Pub., c2000.
Description:	xvii, 508 p. : ill. ; 27 cm.
Language:	English
Subject:	Cancer -- Genetic aspects. Neoplasms -- genetics. Cell Transformation, Neoplastic -- genetics. DNA Repair -- genetics. Genetic Predisposition to Disease. Genes, Suppressor, Tumor. Oncogenes. Cancer -- Genetic aspects.
Format:	Print Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/4259038

Hidden Bibliographic Details
Other authors / contributors:	Ehrlich, Melanie, 1945-
ISBN:	1881299198
Notes:	Includes bibliographical references and index.

Description
Summary:	Ehrlich (biochemistry, Tulane Medical School) presents 31 papers which describe the most important genetic alterations associated with cancer and the mechanisms through which these alterations cause malignant transformation. The papers are organized into sections on: tumor suppressor genes and cancer modifier loci; activation of the oncogenic function of proto-oncogenes and other cancer-promoting genes by mutation or arrangement; DNA repair and cancer; inherited mutation contributing to oncogenesis; DNA methylation, imprinting, and cancer; the contribution of karyotypic instability to cancer formation and tumor progression; and new strategies for cancer therapies. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Physical Description:	xvii, 508 p. : ill. ; 27 cm.
Bibliography:	Includes bibliographical references and index.
ISBN:	1881299198