Rational diagnosis and treatment : evidence-based clinical decision-making /

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Bibliographic Details
Author / Creator:Wulff, Henrik R.
Edition:3rd ed.
Imprint:Oxford ; Malden, MA, USA : Blackwell Science, 2000.
Description:viii, 221 p. : ill.
Language:English
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4262244
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Other authors / contributors:Gøtzsche, Peter C.
ISBN:0632031972
Notes:Includes bibliographical references (p. 207-216) and index.
Table of Contents:
  • Preface
  • Introduction
  • 1. The Foundation of Clinical Decisions
  • The clinical decision process
  • Clinical data
  • Scales of measurement
  • Taking the history
  • The physical examination
  • Paraclinical findings
  • Global assessments
  • 2. The Reliability and Relevance of Clinical Data
  • Clinical data on an interval scale
  • Clinical data on an ordinal scale
  • Clinical data on a binary scale
  • The statistical concept of normality
  • The concept of disease
  • Interpretation and relevance
  • 3. The Disease Classification
  • The historical perspective
  • The theoretical perspective
  • The practical perspective
  • 4. Diagnosis
  • The diagnostic universe
  • Diagnosis of diseases with an accessible defining criterion
  • Diagnosis of diseases with a concealed defining criterion
  • Syndrome diagnosis
  • Three patients
  • Diagnosis in practice
  • 5. Uncontrolled Experience
  • Uncontrolled experience in a pre-scientific era
  • The numerical method
  • The era of laboratory research
  • The spontaneous course of the disease
  • Imprecision of clinical data and regression towards the mean
  • Run of luck
  • Bias
  • The placebo effect
  • The need for controlled experience
  • Alternative medicine: scientific and pseudoscientific thinking
  • 6. The Randomized Clinical Trial
  • Selection of patients
  • Randomization
  • Choice of treatment in the control group
  • Principles of blinding
  • Cross-over trials
  • The choice of outcome measures
  • The statistical analysis
  • Meta-analysis
  • From trials to clinical practice
  • 7. Medicine and the Humanities
  • The four components of clinical reasoning
  • The empathic-hermeneutic component
  • The ethical component
  • Clinical research ethics
  • 8. Critical Reading of Medical Journals
  • Logical analysis of medical papers
  • Descriptive statics
  • Estimation
  • Testing hypotheses
  • Sample size calculations
  • Dr N and Dr R
  • Statistical tests
  • Correlation analysis
  • Life table analysis
  • References
  • Index