Summary: | This state-of-the-science reference provides valuable information on the pathophysiology and economic and social consequences of allergic skin reactions, as well as new treatments based on emerging concepts of skin disease pathobiology-addressing the epidemiology, mechanisms, occupational effects, environmental triggers, and quality-of-life concerns.<br> Focuses on atopic dermatitis, urticaria, and allergic contact dermatitis, among other increasingly common skin disorders. Written by more than 35 leading researchers, Allergic Skin Disease<br> reviews basic principles of the causes of allergic skin responses<br> analyzes the role of key cell types, effector molecules, cytokines, mediators, chemokines, cell adhesion molecules, and immunogenetic mechanisms<br> showcases the dynamics of adhesion molecules and the pathophysiology of pruritus<br> examines clinical features of skin allergies, particularly regarding immune mechanisms that determine pathogenic course and outcome<br> investigates behaviors of keratinocytes, dendritic cells and macrophages, fibroblasts, lymphocytes, granulocytes, and endothelial cells<br> explores phototherapy, photochemotherapy, immunomodulatory therapy, and traditional antiinflammatory therapy for recalcitrant skin diseases<br> discusses anaphylaxis and other allergic reactions to insect bites<br> surveys demographism, vibratory angioedema, and other types of urticaria<br> identifies allergic and infectious triggers of skin disease<br> and more!<br> Containing over 1800 bibliographic citations, Allergic Skin Disease is a must-read resource for dermatologists, allergists, immunologists, pharmaceutical and cosmetic chemists, internists, pediatricians, and graduate and medical school students in these disciplines.
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