The Pharmacology of functional, biochemical, and recombinant receptor systems /

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Bibliographic Details
Imprint:Berlin ; New York : Springer, c2000.
Description:xx, 448 p. : ill. ; 24 cm.
Language:English
Series:Handbook of experimental pharmacology. v. 148
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4325422
Hidden Bibliographic Details
Other authors / contributors:Kenakin, Terrence P.
Angus, James A.
ISBN:3540661247 (hardcover : alk. paper)
Notes:Includes bibliographical references and index.

MARC

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300 |a xx, 448 p. :  |b ill. ;  |c 24 cm. 
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440 0 |a Handbook of experimental pharmacology.  |v v. 148 
504 |a Includes bibliographical references and index. 
505 0 0 |t Introduction: Bioassays - Past Uses and Future Potential /  |r J. W. Black --  |g Sect. I.  |t Classical Pharmacology and Isolated Tissue Systems.  |g Ch. 1.  |t Human Vascular Receptors in Disease: Pharmacodynamic Analyses in Isolated Tissue /  |r J. A. Angus.  |g Ch. 2.  |t Problems in Assigning Mechanisms: Reconciling the Molecular and functional Pathways in [alpha]-Adrenoceptor-Mediated Vasoconstriction /  |r M. J. Lew.  |g Ch. 3.  |t G Protein-Coupled Receptors in Human Heart /  |r A. J. Kaumann --  |g Sect. II.  |t New Theoretical Concepts and Molecular Mechanisms of Receptor Function.  |g Ch. 4.  |t Kinetic Modeling Approaches to Understanding Ligand Efficacy /  |r J. J. Linderman.  |g Ch. 5.  |t The Evolution of Drug-Receptor Models: The Cubic Ternary-Complex Model for G Protein-Coupled Receptors /  |r T. Kenakin, P. Morgan and M. Lutz /  |r [et al.].  |g Ch. 6.  |t Inverse Agonism /  |r R. Bond, G. Milligan and M. Bouvier.  |g Ch. 7.  |t Efficacy: Molecular Mechanisms and Operational Methods of Measurement. A New Algorithm for the prediction of Side Effects /  |r T. Kenakin.  |g Ch. 8.  |t A Look at Receptor Efficacy. From the Signalling Network of the Cell to the Intramolecular Motion of the Receptor /  |r H. O. Onaran, A. Scheer and S. Cotecchia /  |r [et al.].  |g Ch. 9.  |t Mechanisms of Non-Competitive Antagonism and Co-Agonism /  |r D. G. Trist and M. Corsi.  |g Ch. 10.  |t Mechanisms of Receptor Activation and the Relationship to Receptor Structure /  |r D. M. Perez and S. S. Karnik --  |g Sect. III.  |t New Technologies for the Study of Drug Receptor Interaction.  |g Ch. 11.  |t The Assembly of Recombinant Signalling Systems and Their Use in Investigating Signaling Dynamics /  |r S. M. Lanier.  |g Ch. 12.  |t Insect Cell Systems to Study the Communication of Mammalian Receptors and G Proteins /  |r R. T. Windh, A. J. Barr and D. R. Manning.  |g Ch. 13.  |t Altering the Relative Stoichiometry of Receptors, G Proteins and Effectors: Effects on Agonist Function /  |r G. Milligan.  |g Ch. 14.  |t The Study of Drug-Receptor Interaction Using Reporter Gene Systems in Mammalian Cells /  |r D. M. Ignar and S. Rees.  |g Ch. 15.  |t Melanophore Recombinant Receptor Systems /  |r C. K. Jayawickreme and M. R. Lernek. 
650 0 |a Drug receptors  |x Research  |x Methodology. 
650 1 2 |a Receptors, Drug  |x physiology. 
650 2 2 |a Dose-Response Relationship, Drug. 
650 2 2 |a Pharmaceutical Preparations  |x metabolism. 
650 2 2 |a Receptors, Cell Surface  |x drug effects. 
650 2 2 |a Technology, Pharmaceutical  |x methods. 
650 7 |a Drug receptors  |x Research  |x Methodology.  |2 fast  |0 http://id.worldcat.org/fast/fst00898700 
700 1 |a Kenakin, Terrence P.  |0 http://id.loc.gov/authorities/names/n86105077  |1 http://viaf.org/viaf/19854231 
700 1 |a Angus, James A.  |0 http://id.loc.gov/authorities/names/n80117467  |1 http://viaf.org/viaf/27241134 
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