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000404s2000 gw a b 001 0 eng c |
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|a 00036585
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|a 3540661247 (hardcover : alk. paper)
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|a (OCoLC)43854053
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|a NLM
|c NLM
|d OHX
|d OrLoB-B
|d OCoLC
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042 |
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|a pcc
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049 |
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|a CGUA
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060 |
1 |
0 |
|a W1
|b HA51L v.148 2000
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060 |
1 |
0 |
|a QV 38
|b P5367 2000
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069 |
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|a 100941186
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072 |
|
7 |
|a QP
|2 lcco
|
245 |
0 |
4 |
|a The Pharmacology of functional, biochemical, and recombinant receptor systems /
|c contributors, J.A. Angus ... [et al.] ; editors, T. Kenakin and J.A. Angus.
|
260 |
|
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|a Berlin ;
|a New York :
|b Springer,
|c c2000.
|
300 |
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|a xx, 448 p. :
|b ill. ;
|c 24 cm.
|
336 |
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|a text
|b txt
|2 rdacontent
|0 http://id.loc.gov/vocabulary/contentTypes/txt
|
337 |
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|a unmediated
|b n
|2 rdamedia
|0 http://id.loc.gov/vocabulary/mediaTypes/n
|
338 |
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|a volume
|b nc
|2 rdacarrier
|0 http://id.loc.gov/vocabulary/carriers/nc
|
440 |
|
0 |
|a Handbook of experimental pharmacology.
|v v. 148
|
504 |
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|a Includes bibliographical references and index.
|
505 |
0 |
0 |
|t Introduction: Bioassays - Past Uses and Future Potential /
|r J. W. Black --
|g Sect. I.
|t Classical Pharmacology and Isolated Tissue Systems.
|g Ch. 1.
|t Human Vascular Receptors in Disease: Pharmacodynamic Analyses in Isolated Tissue /
|r J. A. Angus.
|g Ch. 2.
|t Problems in Assigning Mechanisms: Reconciling the Molecular and functional Pathways in [alpha]-Adrenoceptor-Mediated Vasoconstriction /
|r M. J. Lew.
|g Ch. 3.
|t G Protein-Coupled Receptors in Human Heart /
|r A. J. Kaumann --
|g Sect. II.
|t New Theoretical Concepts and Molecular Mechanisms of Receptor Function.
|g Ch. 4.
|t Kinetic Modeling Approaches to Understanding Ligand Efficacy /
|r J. J. Linderman.
|g Ch. 5.
|t The Evolution of Drug-Receptor Models: The Cubic Ternary-Complex Model for G Protein-Coupled Receptors /
|r T. Kenakin, P. Morgan and M. Lutz /
|r [et al.].
|g Ch. 6.
|t Inverse Agonism /
|r R. Bond, G. Milligan and M. Bouvier.
|g Ch. 7.
|t Efficacy: Molecular Mechanisms and Operational Methods of Measurement. A New Algorithm for the prediction of Side Effects /
|r T. Kenakin.
|g Ch. 8.
|t A Look at Receptor Efficacy. From the Signalling Network of the Cell to the Intramolecular Motion of the Receptor /
|r H. O. Onaran, A. Scheer and S. Cotecchia /
|r [et al.].
|g Ch. 9.
|t Mechanisms of Non-Competitive Antagonism and Co-Agonism /
|r D. G. Trist and M. Corsi.
|g Ch. 10.
|t Mechanisms of Receptor Activation and the Relationship to Receptor Structure /
|r D. M. Perez and S. S. Karnik --
|g Sect. III.
|t New Technologies for the Study of Drug Receptor Interaction.
|g Ch. 11.
|t The Assembly of Recombinant Signalling Systems and Their Use in Investigating Signaling Dynamics /
|r S. M. Lanier.
|g Ch. 12.
|t Insect Cell Systems to Study the Communication of Mammalian Receptors and G Proteins /
|r R. T. Windh, A. J. Barr and D. R. Manning.
|g Ch. 13.
|t Altering the Relative Stoichiometry of Receptors, G Proteins and Effectors: Effects on Agonist Function /
|r G. Milligan.
|g Ch. 14.
|t The Study of Drug-Receptor Interaction Using Reporter Gene Systems in Mammalian Cells /
|r D. M. Ignar and S. Rees.
|g Ch. 15.
|t Melanophore Recombinant Receptor Systems /
|r C. K. Jayawickreme and M. R. Lernek.
|
650 |
|
0 |
|a Drug receptors
|x Research
|x Methodology.
|
650 |
1 |
2 |
|a Receptors, Drug
|x physiology.
|
650 |
2 |
2 |
|a Dose-Response Relationship, Drug.
|
650 |
2 |
2 |
|a Pharmaceutical Preparations
|x metabolism.
|
650 |
2 |
2 |
|a Receptors, Cell Surface
|x drug effects.
|
650 |
2 |
2 |
|a Technology, Pharmaceutical
|x methods.
|
650 |
|
7 |
|a Drug receptors
|x Research
|x Methodology.
|2 fast
|0 http://id.worldcat.org/fast/fst00898700
|
700 |
1 |
|
|a Kenakin, Terrence P.
|0 http://id.loc.gov/authorities/names/n86105077
|1 http://viaf.org/viaf/19854231
|
700 |
1 |
|
|a Angus, James A.
|0 http://id.loc.gov/authorities/names/n80117467
|1 http://viaf.org/viaf/27241134
|
901 |
|
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|a ToCBNA
|a Analytic
|
903 |
|
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|a HeVa
|
929 |
|
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|a cat
|
999 |
f |
f |
|i 6dfa186a-3ae1-5ba3-83ca-3ad6273bcb58
|s 2b7897c2-e769-581b-a541-56d51af54f8a
|
928 |
|
|
|t Library of Congress classification
|a QP905.H402 v.148
|l ASR
|c ASR-SciASR
|i 4487456
|
927 |
|
|
|t Library of Congress classification
|a QP905.H402 v.148
|l ASR
|c ASR-SciASR
|g Analytic
|e CRERAR
|b A50342531
|i 6909521
|