Bacterial and bacteriophage genetics /

Bacterial and bacteriophage genetics /

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Bibliographic Details
Author / Creator:Birge, Edward A. (Edward Asahel)
Edition:4th ed.
Imprint:New York : Springer, c2000.
Description:xiv, 559 p. : ill. ; 24 cm.
Language:English
Subject:
Bacterial genetics.
Bacteriophages -- Genetics.
Bacterial genetics.
Bacteriophages -- Genetics.
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4327613
Hidden Bibliographic Details
ISBN:0387987304 (acid-free paper)
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface
  • 1. Fundamentals of Bacterial and Viral Genetics
  • Nomenclature
  • Prokaryotic Cells and Eukaryotic Cells
  • Structure
  • Ploidy
  • DNA Structure
  • Chromosome Structure
  • Eukaryotes
  • Prokaryotes
  • Selection: An Essential Element of Microbial Genetics
  • Major Genetic Transfer Processes Observed in Microorganisms and Their Viruses
  • Genetic Transformation
  • Transduction
  • Conjugation
  • Protoplast Fusion
  • Electroporation
  • Bacteriophage Genetic Exchange
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • Reference Books for Specific Organisms
  • 2. Replication and Analysis of DNA
  • DNA Replication
  • Linking DNA in Arbitrary Ways
  • Enzymology of DNA Restriction and Modification
  • Use of Restriction Fragments to Make New DNA Molecules
  • Analytical Techniques for DNA Molecules
  • Electrophoresis
  • Atomic Force Microscopy
  • Detection of Specific DNA Sequences
  • Polymerase Chain Reaction
  • DNA Sequence Analysis
  • Custom Synthesis of DNA
  • Footprinting
  • Gel Mobility Shift Analysis
  • Yeast Two-Hybrid Systems
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 3. Mutations and Mutagenesis
  • Bacterial Variation
  • Plate Spreading
  • Replica Plating
  • Fluctuation Test
  • Measurement of Mutation Rate
  • Expression and Selection of Mutant Cell Phenotypes
  • Expression
  • Selection
  • Genetic Code
  • Kinds of Mutation
  • Base Substitutions
  • Insertion and Deletion Mutations
  • Frameshift Mutations
  • Suppressors of Mutations
  • Mutagens
  • Radiation
  • Chemical Modifiers
  • Base Analogs
  • Cross-Linking Agents
  • Transposons
  • Mutator Mutations
  • Site-Directed Mutagenesis
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 4. Transcription and Translation: Processes and Basic Regulation
  • RNA Structure
  • Transcription
  • RNA Processing
  • Translation of the Genetic Message
  • Ribosome Function
  • Protein Folding
  • Regulation
  • Examples of Regulation in Simple Functional Units
  • Operon: The Basic Regulatory Unit
  • Lactose Operon
  • Galactose Operon
  • Tryptophan Operon
  • Summary
  • Questions for Review and Discussion
  • Suggestions for Further Reading
  • General
  • Specialized
  • 5. DNA Repair and Simple Recombination
  • DNA Repair
  • Mismatch Repair: An Example of Intrareplicational Repair
  • Ultraviolet-Irradiated DNA as a Model Repair System
  • The SOS Global Regulatory Network
  • A Conceptual Model for Generalized Recombination
  • Genetic and Functional Analysis of Recombination
  • RecA and Similar Proteins
  • Other Genes Affecting Recombination
  • A Model for General Recombination
  • Interrelation of Repair and Recombination Pathways
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 6. T4 Bacteriophage as a Model Genetic System
  • Morphology and Composition
  • Experimental Methods Used to Study Phage Infection
  • Genetic Organization of T4
  • Types of Mutations Observed in the T4 Genome
  • Genetic Crosses
  • Visconti-Delbruck Analysis
  • Phage Heterozygotes
  • DNA Replication
  • Molecular Biology of T4 Phage Infection
  • Initial Stages of Infection
  • Regulatory Issues
  • Morphogenesis and Maturation
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 7. Genetics of Other Intemperate Bacteriophages
  • Other Members of the T Series
  • Bacteriophages T2 and T6
  • Bacteriophage T1
  • Bacteriophage T5
  • Bacteriophages T7 and T3
  • Bacteriophages Containing Single-Strand DNA
  • Bacteriophages Belonging to the Ff Group
  • Bacteriophage oX174
  • RNA-Containing Bacteriophages
  • Single-Stranded RNA Viruses
  • Double-Stranded RNA Viruses
  • Bacteriophages Infecting Bacillus subtilis
  • Bacteriophage SP01
  • Bacteriophage o29
  • Bacteriophages Infecting the Archaea
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 8. Genetics of Temperate Bacteriophages
  • General Nature of the Temperate Response
  • Bacteriophage Lambda as the Archetypal Temperate Phage
  • Lytic Life Cycle
  • Temperate Life Cycle
  • Genetic Map of Lambda
  • Other Lambdoid Phages
  • Bacteriophage P22
  • Bacteriophages P2 and P4
  • Bacteriophage P1
  • Bacteriophage Mu
  • SSV1 and SSV2
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 9. Transduction
  • Bacteriophage Lambda: A Specialized Transducing Phage
  • Production of Transducing Particles
  • Physiology and Genetic Consequences of Transduction
  • Lambda Phages That Transduce Additional Genetic Markers
  • Specialized Transducing Phages Other than Lambda
  • Bacteriophage [phi]80
  • Bacteriophage P1
  • Bacteriophage P22
  • Generalized Transduction
  • Bacteriophage P22
  • Bacteriophage P1
  • Other Phages
  • Analysis of Transductional Data
  • Generalized Transduction
  • Specialized Transduction
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 10. Genetic Transformation
  • Standard Genetic Transformation Systems
  • Discovery of Genetic Transformation
  • Competent Cells
  • DNA Uptake and Entry
  • Establishment of Donor DNA in the Recipient Cell
  • Other Transformation Systems
  • Escherichia coli
  • Electroporation
  • Transfection
  • E. coli as a Recipient
  • B. subtilis as a Recipient
  • Genetic Mapping Using Transformation
  • Analysis of Transformational Data
  • Genetic Map for B. subtilis
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 11. Conjugation and the Escherichia coli Paradigm
  • Basic Properties of the E. coli Conjugation System
  • Discovery of Conjugation
  • Discovery of Efficient Donor Strains and Partial Transfer
  • Nature of the Transfer Process
  • Recombination Following Conjugation
  • Construction of the First Genetic Map
  • Interactions of the F Plasmid with the Bacterial Chromosome
  • Integration of the F Plasmid
  • Excision of the F Plasmid
  • Physiology of Conjugation
  • Formation of Mating Aggregates
  • Transfer DNA Synthesis
  • Analysis of the F Plasmid
  • General Structure
  • Genetic Analysis of the F Plasmid
  • Something Completely Different-Possible Diploidy
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 12. Plasmids and Conjugation Systems Other than F
  • Major Chromosome-Mobilizing Plasmids
  • Salmonella
  • Pseudomonas
  • Enterococcus
  • Streptomyces
  • Agrobacterium
  • Sulfolobus
  • Bacteriocins
  • General Properties
  • Colicins: The Best-Studied Bacteriocins
  • Conjugative Colicin Plasmids
  • Nonconjugative Colicin Plasmids
  • Resistance Plasmids
  • General Properties
  • Plasmid R100
  • Genetic Analysis of Plasmid R100
  • Conjugal Plasmid Interactions
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 13. Plasmid Molecular Biology
  • Plasmid DNA Replication
  • Interactions Between Plasmid and Host
  • DNA Replication Processes
  • Control of Copy Number
  • Partitioning
  • Incompatibility
  • Conjugal Functions
  • Pilus Production
  • Transfer DNA Replication
  • Broad Host Range Plasmids
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 14. Advanced Regulatory Topics
  • Regulons
  • Maltose
  • Heat Shock Proteins
  • Global Regulatory Networks
  • Nitrogen Regulation
  • Endospore Formation in Bacillus
  • Inteins
  • Small RNA Molecules
  • Summary
  • Questions for Review and Discussion
  • References
  • Generalized
  • Specialized
  • 15. Site-Specific Recombination
  • General Principles
  • Double Site-Specific Recombination
  • Phage Lambda Integration
  • Circular Chromosome Segregation
  • Inversion Systems
  • Integrons
  • Transposons: Single Site-Specific Recombination
  • Transposon Tn10
  • Phage Mu Transposition
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 16. Applied Bacterial Genetics
  • More Information About Recombinant DNA Technology
  • Restriction Mapping
  • Sources of DNA for Linking
  • Safety Considerations
  • Difficulties with the Expression of Cloned DNA
  • Cloning Vectors
  • Phage [lambda] Vectors
  • Phage M13 Vectors
  • Expression Vectors
  • Broad Host Range Vectors
  • Runaway Replication Vectors
  • Artificial Chromosomes
  • Applications of DNA Cloning
  • Peptide Display Systems
  • Laboratory Reagents
  • Phage as Therapeutic Agents
  • Other Applications of Bacterial Genetics
  • Mutagenicity Testing
  • Recombineering
  • Genetic Transfer in Nature
  • Ecogenomics
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • 17. Bacterial and Bacteriophage Evolution
  • What Is Evolution?
  • Implications of Strain Differences
  • Cryptic Genes
  • Expression of Evolutionary Relationships
  • Genomics and Proteomics
  • Bacteria
  • Bacteriophage
  • Specific Examples of Evolution
  • Evolution of Genomes
  • Evolution of the Genetic Code
  • Evolution of Proteins
  • Evolution of Regulatory Sequences
  • Evolution of Mitochondria and Other Endosymbionts
  • Genetic Structure of the Chromosome
  • Bacteria
  • Bacteriophage
  • Summary
  • Questions for Review and Discussion
  • References
  • General
  • Specialized
  • Appendix 1. Laws of Probability and Their Application to Prokaryote Cultures
  • Appendix 2. Useful World Wide Web Sites for Bacterial Genetics
  • Appendix 3. Answers to Application Questions
  • Glossary
  • Index
The Sumner Mayburg Library Fund, established with a bequest from her estate bookplate
The John Crerar Library bookplate

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