Heart physiology and pathophysiology /

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Bibliographic Details
Edition:4th ed.
Imprint:San Diego, Calif. ; London : Academic Press, 2001.
Description:xxi, 1261 p., [1] leaf of plates : ill. (some col.) ; 29 cm.
Language:English
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4345320
Hidden Bibliographic Details
Other title:Physiology and pathophysiology of the heart.
Other authors / contributors:Sperelakis, Nick, 1930-
ISBN:0126569754 (alk. paper)
Notes:Previous ed.: published as Physiology and pathophysiology of the heart. Boston; London: Kluwer Academic, 1995.
Includes bibliographical references and index.
Table of Contents:
  • Contributors
  • Foreword
  • Preface
  • Part I. Pumping Action and Electrical Activity of the Heart
  • 1. Sequence of Cardiac Activation and Ventricular Mechanics
  • 2. Coronary Circulation and Hemodynamics
  • 3. Neurohumoral Control of Cardiac Function
  • 4. Control of Cardiac Output and its Alterations during Exercise and in Heart Failure
  • 5. Ultrastructure of Cardiac Muscle and Blood Vessels
  • 6. Excitability and Impulse Propagation
  • 7. Electrocardiogram and Cardiac Excitation
  • 8. Gap-Junction Channels and Healing-Over of Injury
  • Part II. Cellular Electrophysiology of Heart and Vascular Smooth Muscle
  • 9. Electrogenesis of the Resting Potential
  • 10. Cardiac Action Potentials
  • 11. Electrophysiology of Vascular Smooth Muscle
  • 12. Sodium Channels
  • 13. Voltage-Dependent Calcium Channels
  • 14. Voltage-Dependent K+ Channels
  • 15. Inwardly-Rectifying K+ Channels in the Heart
  • 16. Voltage and Calcium-Activated K+ Channels of Coronary Smooth Muscle
  • 17. Ion Channels in Vascular Smooth Muscle
  • 18. Cardiac Pacemaker Currents
  • 19. Chloride Channels in Heart
  • 20. Regulation of Cardiac Ion Channels by Phosphorylation, Ca2+, Cytoskeleton, and Stretch
  • Part III. Pumps And Exchangers
  • 21. Cardiac Na+/K+ Pump
  • 22. Cardiac Na+-Ca2+ Exchanger: Pathophysiology and Pharmacology
  • 23. Na+/H+ Exchanger and pH Regulation
  • 24. Transport in Nucleus
  • 25. Sarcoplasmic Reticulum Ca2+ Transport
  • 26. Calcium Release from Cardiac Sarcoplasmic Reticulum
  • Part IV. Vascular Endothelium
  • 27. Function of Vascular Endothelium
  • 28. Ion Channels in Vascular Endothelium
  • Part V. Excitation-Contraction Coupling and Pharmacomechanical Coupling
  • 29. Electromechanical and Pharmacomechanical Coupling in Vascular Smooth Muscle Cells
  • 30. Mechanisms Regulating Cardiac Myofilament Response to Calcium
  • 31. Vascular Smooth Muscle Contraction
  • Part VI. Metabolism and Energetics
  • 32. Myocardial Energy Metabolism
  • 33. Metabolism and Energetics of Vascular Smooth Muscle
  • Part VII. Signaling Systems
  • 34. Adrenergic Receptors in the Cardiovascular System
  • 35. Cardiac Action of Angiotensin II
  • 36. ATP and Adenosine Signal Transductions
  • 37. Kinase Signaling in the Cardiovascular System
  • 38. Calcium Signaling
  • 39. Diadenosine Polyphosphate Signaling in the Heart
  • Part VIII. Developmental Changes and Aging
  • 40. Cardiac Development and Regulation of Cardiac Transcription
  • 41. Developmental Changes of Ion Channels
  • 42. Aging of the Cardiovascular System
  • 43. Changes in Autonomic Responsiveness during Development
  • Part IX. Mechanism of Action of Cardioactive Drugs
  • 44. Inotropic Mechanism in Cardiac Muscle
  • 45. Mechanisms of Action of Calcium Antagonists
  • 46. Cyclic Nucleotides and Protein Phosphorylation in Vascular Smooth Muscle Relaxation
  • 47. K+ Channel Openers
  • 48. Mode of Action of Antiarrhythmic Drugs
  • Part X. Pathophysiology
  • 49. Cellular Mechanisms of Cardioprotection
  • 50. Ischemic Preconditioning: Description, Mechanism, and Significance
  • 51. Cardioplegia and Surgical Ischemia
  • 52. Apoptosis
  • 53. Calcium Overload in Ischemia/Reperfusion Injury
  • 54. Coronary Atherosclerosis and Restenosis
  • 55. Diabetic Vascular Disease
  • 56. Angiogenesis and Coronary Collateral Circulation
  • 57. Molecular Pathophysiology of Cardiomyopathies
  • 58. Signal Transduction of Cardiac Myocyte Hypertrophy
  • 59. Electrophysiological Changes in Hypertrophy
  • 60. Molecular Basis of Inherited Long QT Syndromes and Cardiac Arrhythmias
  • 61. Molecular Mechanisms of Atrial Fibrillation
  • 62. Lipids Released during Ischemia and Arrhythmogenesis
  • 63. Ion Channels in the Heart
  • 64. Cardiac Arrhythmias: Reentry and Triggered Activity
  • 65. Myocardial Reperfusion Injury-Role of Free Radicals and Mediators of Inflammation
  • 66. Cardiac Toxicology
  • 67. Regulation of Gene Expression by Hypoxia
  • 68. Gene Transfer in Cardiovascular Therapy
  • Index