The skin and gene therapy /

The skin and gene therapy /

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Bibliographic Details
Imprint:	Berlin ; New York : Springer, c2001.
Description:	xix, 301 p. : ill. (some col.) ; 24 cm.
Language:	English
Subject:	Skin -- Diseases -- Gene therapy. Skin -- Diseases -- Immunotherapy. Skin Diseases -- immunology. Gene Therapy -- methods. Genetic transformation. Skin Diseases -- therapy.
Format:	Print Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/4378851

Hidden Bibliographic Details
Other authors / contributors:	Hengge, Ulrich R., 1963- Volc-Platzer, Beatrix, 1954-
ISBN:	3540667601
Notes:	Includes bibliographical references and index.

Description
Summary:	Basic Aspects.- 1 The Epidermal Barrier and Strategies for Surmounting It: An Overview.- 2 Stem Cells, Differentiation and Renewal Kinetics of Keratinocytes: Implications for Cutaneous Gene Therapy.- 3 Relevant Animal Models for Skin Gene Therapy.- 4 Nonviral Gene Transfer into the Skin.- 5 Safety and Pharmacokinetics of Naked Plasmid DNA: Studies on Dissemination and Ectopic Expression.- 6 Uptake of DNA by Keratinocytes.- Treatment of Skin Diseases.- Gene Therapy of Inherited Skin Diseases.- Gene Transfer Strategies in Tissue Repair.- Systemic Effects of Skin Gene Therapy.- The Use of Skin-Directed Gene Therapy in the Treatment of Systemic Diseases.- Keratinocyte Gene Therapy Using Cytokine Genes.- Genetic Vaccination Using the Skin.- Principles of Genetic Immunization.- Systematic Modulation of Immune Responses by CpG DNA.- Genetic and Dendritic Cell Vaccination as a Novel Therapy for Melanoma.- Molecular Strategies Interfering with Tumor Progression of Melanoma and Improving Anti-Tumor Immunity.- Prophylactic and Therapeutic DNA Vaccines Against Infectious Diseases.
Physical Description:	xix, 301 p. : ill. (some col.) ; 24 cm.
Bibliography:	Includes bibliographical references and index.
ISBN:	3540667601