Cooperativity and regulation in biochemical processes /
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| Author / Creator: | Ben-Naim, Arieh, 1934- |
|---|---|
| Imprint: | New York : Kluwer Academic/Plenum Publishers, c2001. |
| Description: | xvii, 349 p. : ill. ; 24 cm. |
| Language: | English |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4428305 |
Table of Contents:
- 1. Introducing the Fundamental Concept
- 2. The Binding Isotherm (BI)
- 3. Adsorption on a Single Polymer with Conformation Changes Induced by the Binding Process
- 4. Two-site Systems; Direct and Indirect Cooperativity
- 5. Three-site Systems; Non-additivity and Long Range Correlations
- 6.
- 7. Large Linear Systems of Binding Sites
- 8. Regulatory Enzymes
- 9. Solvent Effects on Cooperativity
- 10. Appendices
- Appendix A. Pair and triple correlations between events
- Appendix B. Localization of the adsorbent molecules, and its effect on the binding isotherm
- Appendix C. Transition from microstates to macrostates
- Appendix D. First order correction to non-ideality of the ligand's reservoir
- Appendix E. Relative slopes of the equilibrated and "frozen in" BI's in a multi macrostate system
- Appendix F. Spurious cooperativity in single-site systems
- Appendix G. The relation between the binding isotherm and the titration curves for two-site systems
- Appendix H. Synthetic data
- Appendix I. A comment on nomenclature
- Appendix J. Average binding constants and correlation functions
- Appendix K. Utility function in binding systems
